Mullerian adenosarcoma of the cervix: case report
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20164690Keywords:
Adenosarcoma, Cervix, Mullerian, PolypAbstract
Mullerian adenosarcomas are rare tumours that may be found in any part of the female genital tract including cervix. They are more common in the reproductive age group and rare among blacks. When they present in the cervix they may be clinically misdiagnosed as an endocervical polyp and histologically as an adenofibroma. Clinical presentation is mostly as irregular vagina bleeding and as a mass in the vagina. Meticulous histopathological evaluation is crucial for its optimum management.
References
Charfi S, Kallel R, Mnif H, Ellouze S, Dhouib M, Guermazi M, et al. Mullerian adenosarcoma of the cervix with sarcomatous overgrowth and heterologous elements presenting as a recurrent cervical polyp. Case Rep Obstet Gynecol. 2012;2012:358302.
Park HM, Park MH, Kim YJ, Chun SH, Ahn JJ, Kim CI, et al. Mullerian adenosarcoma with sarcomatous overgrowth of the cervix presenting as cervical polyp: a case report and review of the literature. Int J Gynecol Cancer. 2004;14:1024-9.
Comunoglu N, Comunoglu C, Bassullu N, Somunkiran A, Calay Z. Mullerian adenosarcoma with sarcomatous overgrowth of the cervix: unusual large polypoid mass. Ups J Med Sci. 2007;112:67-72.
Duggal R, Nijhawan R, Aggarwal N, Sikka P. Mullerian adenosarcoma (heterologous) of the cervix with sarcomatous overgrowth: a case report with review of literature. J Gynecol Oncol. 2010;21:125-8.
Manoharan M, Azmi MA, Soosay G, Mould T, Weekes AR. Mullerian adenosarcoma of uterine cervix: report of three cases and review of literature. Gynecol Oncol. 2007;105:256-60.
Patrelli TS, Gizzo S, Di Gangi S, Guidi G, Rondinelli M, Nardelli GB. Cervical Mullerian adenosarcoma with heterologous sarcomatous overgrowth: a fourth case and review of literature. BMC cancer. 2011;11:236.
Roth LM, Pride GL, Sharma HM. Mullerian adenosarcoma of the uterine cervix with heterologous elements: a light and electron microscopic study. Cancer. 1976;37:1725-36.
Martinelli G, Pileri S, Bazzocchi F, Serra L. Mullerian adenosarcoma of the uterus: a report of 5 cases. Tumori. 1980;66:499-506.
Zaloudek CJ, Norris HJ. Adenofibroma and adenosarcoma of the uterus: a clinicopathologic study of 35 cases. Cancer. 1981;48:354-66.
Chen KT. Rhabdomyosarcomatous uterine adenosarcoma. Int J Gynecol Pathol. 1985;4:146-52.
Gal D, Kerner H, Beck D, Peretz BA, Eyal A, Paldi E. Mullerian adenosarcoma of the uterine cervix. Gynecol Oncol. 1988;31:445-53.
Kerner H, Lichtig C. Mullerian adenosarcoma presenting as cervical polyps: a report of seven cases and review of the literature. Obstet Gynecol. 1993;81:655-9.
Gast MJ, Radkins LV, Jacobs AJ, Gersell D. Mullerian adenosarcoma of the cervix with heterologous elements: diagnostic and therapeutic approach. Gynecol Oncol. 1989;32:381-4.
Zichella L, Perrone G, De Falco V, Pelle R, Eleuteri Serpieri D. Heterologous mesodermal adenosarcoma of the endocervix. Description of a clinical case. Minerva Ginecol. 1994;46:511-4.
Jones MW, Lefkowitz M. Adenosarcoma of the uterine cervix: a clinicopathological study of 12 cases. Int J Gynecol Pathol. 1995;14:223-9.
Feroze M, Aravindan KP, Thomas M. Mullerian adenosarcoma of the uterine cervix. Indian J Cancer. 1997;34:68-72.
Clement PB, Zubovits JT, Young RH, Scully RE. Malignant mullerian mixed tumors of the uterine cervix: a report of nine cases of a neoplasm with morphology often different from its counterpart in the corpus. Int J Gynecol Pathol. 1998;17:211-22.
Ramos P, Ruiz A, Carabias E, Pinero I, Garzon A, Alvarez I. Mullerian adenosarcoma of the cervix with heterologous elements: report of a case and review of the literature. Gynecol Oncol. 2002;84:161-6.
Bagga R, Keepanasseril A, Srinivasan R, Dey P, Gainder S, Saha SC, et al. Adenosarcoma of the uterine cervix with heterologous elements: a case report and review of literature. Arch Gynecol Obstet. 2010;281:669-75.
Chin PS, Chia YN, Lim YK, Yam KL. Diagnosis and management of Mullerian adenosarcoma of the uterine cervix. Int J Gynecol Obstet. 2013;121:229-32.
Olutoyin G Omoniyi-Esan, Olusola B Fasubaa, Kayode A Adelusola, Olusegun S Ojo. Histological Pattern of Cervical Malignancies in Southwestern Nigeria. Trop J Obstet and Gynaecol. 2004;21:118-21.
McCluggage WG. Mullerian Adenosarcoma of the Female Genital Tract. Advances Anatomical Pathology. 2010;17:122-9.
Gillardo A, Prat J. Mullerian adenosarcoma: a clinicopathologic and immunohistochemical study of 55 cases challenging the existence of adenofibroma. Am J Surg Pathol 2009;33:278-288.
Fleming NA, Hopkins L, de Nanassy J, Senterman M, Black AY. Mullerian adenosarcoma of the cervix in a 10-year-old girl: case report and review of the literature. 2009;22:45-51.
