Pregnancy outcomes after spontaneous conception with previous spontaneous abortion preceding present pregnancy


  • Shree Kant Dadheech Department of Obstetrics and Gynecology, Armed Forces Medical College, Pune, Maharashtra, India
  • Meenakshi K. Bharadwaj Department of Obstetrics and Gynecology, Armed Forces Medical College, Pune, Maharashtra, India
  • Brig Aruna Menon Department of Obstetrics and Gynecology, Armed Forces Medical College, Pune, Maharashtra, India



Spontaneous abortion, Preterm birth, Cesarean delivery, Spontaneous conception


Background: The objective of the present study was to study pregnancy outcomes in patients with Spontaneous conception with history of previous spontaneous abortion preceding present pregnancy.

Methods: A prospective study included patients with spontaneous conception with history of previous spontaneous abortion preceding present pregnancy admitted in the department of obstetrics and gynecology, command hospital, Pune between October 2018 and April 2020. The patients were booked (minimum 3 visits in antenatal outdoor clinic) or admitted for the first time as an emergency. The detailed history about previous abortions was taken and routine as well as investigations for possible etiologies of previous abortions were done. Cases with history of mid-trimester abortion were investigated for cervical incompetence. All the patients were observed for complications during present pregnancy like threatened abortion, preeclampsia, preterm labour, intrauterine death and final outcome.

Results: A total of 110 patients with history of previous spontaneous abortion were admitted, all patients were booked. Majority (51.8 %) of patients belong to the age group 25-30 years. All patients were with history of previous one abortion followed by pregnancy with spontaneous conception. The final outcomes were term live birth (86.4%), abortion (8.2%), preterm delivery (5.4%), and no still birth. Caesarian section was done in 32.7% patients for various indications.

Conclusions: Previous history of spontaneous abortion is associated with adverse pregnancy outcome. There is increased risk of abortion, preterm delivery, need for caesarean sections and fetal loss in cases of previous spontaneous abortions. These complications and fetal loss can be reduced by booking the patients and giving due antenatal care.


Morales C, Sánchez A, Bruguera J, Margarit E, Borrell A, Borobio V et al. Cytogenetic study of spontaneous abortions using semi-direct analysis of chorionic villi samples detects the broadest spectrum of chromosome abnormalities. Am J Med Genet Part A. 2008;146:66.

Janowicz-Grelewska A, Sieroszewski P. Prognostic significance of subchorionic hematoma for the course of pregnancy. Ginekol Polska. 2013;84:944-9.

Lemmers M, Verschoor MAC, Hooker AB, Opmeer BC, Limpens J, Huirne JAF. Dilatation and curettage increases the risk of subsequent preterm birth: A systematic review and meta-analysis. Hum Reprod. 2016;31(1):34-45.

Svare JA, Andersen LF, Langhoff-Roos J, Jensen ET, Bruun B, Lind I. The relationship between prior cervical conization, cervical microbial colonization and preterm premature rupture of the membranes. Eur J Obstet Gynecol Reprod Biol. 1992;47(1):41-5.

Zhou W, Sorensen HT, Olsen J. Induced abortion and low birthweight in the following pregnancy. Int J Epidemiol. 2000;29(1):100-6.

Watson LF, Rayner J, King J, Jolley D, Forster D. Intracervical procedures and the risk of subsequent very preterm birth: A case-control study. Acta Obstet Gynecol Scand. 2012;91(2):204-10.

Molin A. Risk of damage to the cervix by dilatation for first-trimester-induced abortion by suction aspiration. Gynecol Obstet Invest. 1993;35(3):152-4.

Ancel PY, Lelong N, Papiernik E, Saurel-Cubizolles MJ, Kaminski M. EUROPOP History of induced abortion as a risk factor for preterm birth in European countries: results of the EUROPOP survey. Hum Reprod. 2004;19(3):734-40.

Goldzieher JW, Benign BB. The treatment of threatened and recurrent abortion: a critical review. Am J Obstet Gynecol. 1958;75:1202-14.

Warburton D, Fraser FC. Spontaneous abortion risks in man: data from reproductive histories collected in a medical genetics’ unit. Am J Hum Genet. 1964;16:1-25.

Poland BJ, Miller JR, Jones DC, Trimble BK. Reproductive counseling in patients who have had a spontaneous abortion. Am J Obstet Gynecol. 1977;127:685-91.

Naylor AF, Warburton D. Sequential analysis of spontaneous abortion. II. Collaborative study data show that gravidity determines a very substantial rise in risk. Fertil Steril. 1979;31:282-6.

Bakshi K, Rani TU, Kumar PP, Prabhakar G. Risk of adverse pregnancy outcomes after prior spontaneous abortion. Current Med Res Practice. 2015;5:258-61.

Adeniran AS, Fawole AA, Abdul IF, Adesina KT. Spontaneous abortions (miscarriages): Analysis of cases at a tertiary center in North Central Nigeria. J Med Trop. 2015;17:22-6.

Abeysena C. Risk factors for spontaneous abortion. J College Community Physicians of Sri Lanka. 2009;14(1):14-9.

Agrawal S, Agrawal V, Suhane R. Pregnancy outcome following spontaneous abortions. Int J Reprod Contracept Obstet Gynecol. 2015;4:1891-3.

Bhattacharya S, Townend J, Shetty A, Campbell D, Bhattacharya S. Does miscarriage in an initial pregnancy lead to adverse obstetric and perinatal outcomes in the next continuing pregnancy? BJOG. 2008;115:1623-9.

Eras JL, Saftlas AF, Triche E, Hsu CD, Risch HA, Bracken MB. Abortion and its effect on risk of preeclampsia and transient hypertension. Epidemiology. 2000;11(1):36-43.

Kashanian M, Akbarian AR, Baradaran H, Shabandoust SH. Pregnancy outcome following a previous spontaneous abortion (miscarriage). Gynecol Obstetric Investig. 2006;61(3):167-70.

Thorn DH. Spontaneous abortion and subsequent adverse birth outcomes. Am J obstet gvnecol. 1992;166:111-6.






Original Research Articles