Cervical Pap smear study and its utility in cancer screening in patients attending out-patient department in a tertiary care hospital


  • Paridhi Garg Department of Obstetrics and Gynecology, Rama Medical College Hospital and Research Centre, Hapur, Uttar Pradesh, India
  • Shweta Mishra Department of Obstetrics and Gynecology, Rama Medical College Hospital and Research Centre, Hapur, Uttar Pradesh, India
  • Pragati Divedi Department of Obstetrics and Gynecology, Rama Medical College Hospital and Research Centre, Hapur, Uttar Pradesh, India




Cervical cancer, Screening, Bethesda system, Pap smear


Background: Cervical cancer is one of the major causes of mortality among women worldwide. By simple pap screening test cervical cancer and its precursor lesions can be detected and treated early. The aim of the study was to determine and analyze Pap smear reports from women presenting with various gynaecological indications in a tertiary care hospital.

Methods: This retrospective study was conducted in the department of obstetrics and gynaecology at Rama Medical College Hospital and Research Centre, Hapur over a period of 6 months. Patients with various complaints between ages 21 to 70 years were screened during August 2020 to January 2021 by taking Pap smear using Ayres spatula. Total 330 patients were studied.  Slides were reported according to the 2014 Bethesda system.

Results: Maximum number of cases were in the age group 31-40 years constituting 32.72% of the total cases followed by age group 41-50 years. Vaginal discharge was the commonest chief complaint seen in 32.12% cases followed by menorrhagia. Maximum number of cases reported as non-specific inflammatory smears (64.54%). Among epithelial cell abnormalities incidence of LSIL was 2.42% followed by ASCUS (1.82%).

Conclusions: Pap smear testing is an economical, non-invasive and simple OPD procedure to detect potentially precancerous and cancerous lesions of cervix. It should be established as a routine screening procedure to reduce the treatment burden, morbidity and mortality.


Kalkar R, Kulkarni Y. Screening for cervical cancer: an overview. Obstet Gynecol India. 2006;56(2):115-22.

National Cancer Regitry Program. Annual Report, 2021. Available at: https://www.ncdirindia.org/ NCRP/AReports.aspx. Accessed on 20 June 2021.

Khan MS, Raja FY. Pap smear Screening for Precancerous conditions of the cervical cancers. Pak J Med Res. 2005;44(3):111-3.

Mehmetoglu HC, Sadikoglu G, Ozcakir A, Bilgel N. Pap smear screening in the primary health care setting: A study from Turkey. N Am J Med Sci. 2010;2(10):467-72.

International Network for Cancer Treatment and Research. A Practical Manual on Visual Screening for Cervical Neoplasia, 2003. Available at: https://screening.iarc.fr/viavilimanual.pdf. Accessed on 20 June 2021.

Idestrom M, Milsom I, Ellstrom A. Women's experience of coping with a positive Pap smear: A register-based study of women with two consecutive Pap smears reported as CIN 1. Acta Obstet Gynecol Scand. 2003;82(8):756-61.

Pradhan B, Pradhan SB, Mital VP. Correlation of PAP smear findings with clinical findings and cervical biopsy. Kathmandu Univ Med J. 2007;5(4):461-7.

Nayar R, Wilbur DC. The Pap test and Bethesda 2014. Cancer Cytopathol. 2015;123(5):271-81.

Bishop A, Sherris J, Tsu VD, Brook M. Cervical dysplasia treatment: key issues for developing countries. Bull Pan Am Health Organ. 1996;30(4):378-86.

Bamanikar SA, Baravkar DS, Chandanwale SS, Dapkekar P. Study of Cervical Pap smears in a Tertiary Hospital. Indian Med Gazette. 2014;250-4.

Patel MM, Pandya AN, Modi J. Cervical Pap smear study and its utility in cancer screening, to specify the strategy for cervical cancer control. National J Community Med. 2011;2(1):49-51.

Verma A, Verma S, Vashist S, Attri S, Singhal A. A study on cervical cancer screening in symptomatic women using Pap smear in a tertiary care hospital in rural area of Himachal Pradesh, India. Middle East Fertility Society J. 2017;22:39-42.

Sachan PL, Singh M, Patel ML, Sachan R. A Study on Cervical Cancer Screening Using Pap Smear Test and Clinical Correlation. Asia Pac J Oncol Nurs. 2018;5(3):337-41.

Lakshmi PV, Gouri SRS. Study and analysis of 200 cervical Pap smears in our hospital. IJCMR. 2016;3:2787-9.

Idestrom M, Milsom I, Ellstrom A. Knowledge and attitudes about the Pap-smear screening program: a population-based study of women aged 20-59 years. Acta Obstet Gynecol Scand. 2002;81:962-7.






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