Validation the sensitivity and specificity of diabetes in pregnancy study group of India recommended 75 g oral glucose challenge test by comparing with carpenter and couston 100 g oral glucose tolerence test

Shashikala H. Gowda, Tarigopula Swathi, Rakshitha B.


Background: Diabetes is one of the most common non communicable diseases globally. India is considered as the world diabetes capital. Women detected with gestational diabetes mellitus (GDM) have an increased incidence of developing diabetes; especially type 2 diabetes mellitus in the later life, and future development of obesity and diabetes in the offspring. So the aim of this study is to validate the sensitivity and specificity of diabetes in pregnancy study group of India (DIPSI) recommended 75 g oral glucose challenge test (OGCT) by comparing with carpenter and couston 100 g oral glucose tolerance test (OGTT) and to note the prevalence of gestational diabetes in antenatal population attending Kempegowda Institute of Medical Sciences (KIMS).

Methods: All antenatal patients reporting to our hospital at or before 24 to 28 weeks period of gestation will be recruited for the study. Patients at random will be subjected to 75g glucose load according to DIPSI criteria and one week later to carpenter and couston 100 g OGTT. Blood glucose is estimated from venous blood using glucose oxidase and peroxidase (GOD-POD) method and patients diagnosed according to respective criteria.

Results: Most of the patients were in age distribution of 20–25 years. Among 100 patients in study group 28 were diagnosed as GDM by DIPSI criteria. Among 100 patients, 12 patients were detected as GDM by carpenter and couston GTT, 19 patients had impaired glucose tolerance. The incidence of GDM in the antenatal population attending KIMS hospital between gestational ages of 24–28 weeks is 12%.

Conclusions: DIPSI can be used as a diagnostic test for GDM as one step simple and easy procedure especially I low resource settings like India for improved pregnancy outcome.


Intravenous iron sucrose, Iron carboxymaltose, Postpartum anaemia, Haemoglobin, Serum ferritin

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