Incidence of post-operative (caesarean section) infectious morbidities in cleansing and non-cleansing group after povidone iodine vaginal cleaning


  • Pragya Verma Department Obstetrics and Gynecology, Regency Hospital- IVF Unit, Kanpur, Uttar Pradesh, India
  • Dolly Chawla Department Obstetrics and Gynecology, Dr. Baba Sahaib Ambedkar Medical College and Hospital, New Delhi, India
  • Rashmi Khatri Department Obstetrics and Gynecology, Dr. Baba Sahaib Ambedkar Medical College and Hospital, New Delhi, India
  • Preeti Verma Department of Community Medicine, Government Medical College, Kannauj, Uttar Pradesh, India



Caesarean section, Post-operative infectious morbidities (endometritis), Cleansing and non-cleansing group, Povidone iodine


Background: Despite of wide spread use of prophylactic antibiotics and various antiseptic measures, post-operative infection remains one of the significant and serious complication of caesarean delivery contributing to high maternal morbidity and mortality. Objective was to study the incidence of post-operative infectious morbidities in patients with/without povidone iodine vaginal cleansing done prior to caesarean section.

Methods: A prospective randomized control study was done in the department of obstetrics and gynecology of Dr. Baba Saheb Ambedkar Medical College and Hospital, New Delhi.

Results: Mean age of participants in group A is 26.22±2.47 years and in group B is 26.48±2.3 years. Majority women (84.0%) underwent emergency lower segment caesarean section (LSCS). (6.4%) women developed post-operative endometritis, out of which maximum (4.6%) belong to no vaginal cleansing group (B) compared to 1.8% in povidone iodine vaginal cleansing group(A), which is statistically significant (p=0.01). Over all (13%) women had post-operative fever, with significant difference among the two groups i.e. (8.6%) were in group B versus (4.4%) in group A (p=0.005).

Conclusions: Povidone iodine vaginal cleansing prior to caesarean section is significantly effective in reducing post-operative infectious morbidities.


Caesarean section: A brief history part1/national library of medicine. Available at https://www.nih. gov/exhibition/caesarean/part1.html. Accessed on 24 January 2021.

Radhakrishnan T,Vasanthakumari K.P, Babu P.k. increasing trend of caesarean section rates in India: evdence from NFHS- 4.JMSCR.august 2017;5(8):2616-7.

Reidd VC, Hartmann KE, McMahon M, Fry EP. Vaginal preparation with povidone iodine and post caesarean infectious morbidity: a randomized controlled trial. Obstet Gynecol. 2001;97:147-52.

Smaill F, Hofmeyr GJ. Antibiotic prophylaxis for caesarean section. Cochrane Database Syst Rev. 2002:CD000933.

Memon S, Qazi RA, Bibi S, Parveen NE. Effect of preoperative vaginal cleansing with an antiseptic solution to reduce post caesarean infectious morbidity. J Pakistan Medical Association. 2011;61(12):1179-83.

Starr RV, Zurawski J, Ismail M. Preoperative vaginal preparation with povidoneiodine and the risk of postcesarean endometritis. Obstet Gynecol. 2005;105(5):1024-9.

Yildirim G, Gungorduk K, Asicioglu O, Basaran T, Temizkan O, Davas I, et al. Does vaginal preparation with povidone-iodine prior to caesarean delivery reduce the risk of endometritis? a randomized controlled trial. Am J Obstet Gynecol. 2017;216 (1).

Asad S, Batool Mazhar S, Khalid Butt N, Habiba U . Vaginal cleansing prior to caesarean section and postoperative infectious morbidity. Br J Obstet Gynecol. 2017;124:45.






Original Research Articles