DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20170060

Prevalence of antenatal vulvovaginal candidiasis: our experience

Arul Anne Rose S., Sony Paul, Iyanar Kannan

Abstract


Background: The objective of our study is to determine the prevalence of vulvovaginal candidiasis and influence of maternal age, parity or trimester on its occurrence among pregnant women, attending the antenatal clinic in our teaching hospital. It helps us to understand the magnitude of the problem in our region and to implement the necessary treatment modalities to reduce the preterm births attributed to vaginal candidiasis.

Methods: It was a hospital based prospective study over a period of six months. High vaginal swabs were collected from the pregnant patients after getting consent and sent for culture. Candida positive cases were noted and results were analysed.

Results: A total of 200 high vaginal swabs were collected and reported in our study. Among them 108 swabs were positive for Candida growth (54%) and 92 swabs were negative for growth (46%). Culture positive patients clinical details were analyzed and statistical significance was noted (based on age group, parity and trimester).

Conclusions: Our study concluded that candidiasis is more prevalent in pregnant women but there was no statistical significance in occurrence of vaginal candidiasis among various age groups, parity or trimester. Hence it is better to screen all the patients in I/ early II trimester in order to find out and treat positive cases early to prevent preterm births attributed to vaginal candidiasis.


Keywords


Preterm birth, Pregnancy, Vulvo vaginal candidiasis

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References


Kiss H, Petricevic L, Husslein P. Prospective randomised controlled trial of an infection screening programme to reduce the rate of preterm delivery. British Medical Journal. 2004;329(7462):371.

Cotch MF, Hillier SL, Gibbs RS, Eschenbach DA. Epidemiology and outcomes associated with moderate to heavy Candida colonization during pregnancy. Vaginal Infections and Prematurity Study Group. Am J Obstet Gynecol. 1998;178 (2):374-80.

Chaim W, Mazor M, Wiznitzer A. The prevalence and clinical significance of intraamniotic infection with Candida species in women with preterm labor. Arch Gynecol Obstet. 1992;251(1):9-15.

Figueroa R, Garry D, Elimian A, Patel K, Sehgal PB, Tejani N. Evaluation of amniotic fluid cytokines in preterm labor and intact membranes. J Matern Fetal Neonatal Med. 2005;18(4):241-7.

Mendling W, Brasch J. German Society for Gynecology and Obstetrics; Working Group for Infections and Infect immunology in Gynecology and Obstetrics; German Society of Dermatology, the Board of German Dermatologists; German Speaking Mycological Society. 2010.

Guideline vulvovaginal candidiasis of the German Society for Gynecology and Obstetrics, the Working Group for Infections and Infect immunology in Gynecology and Obstetrics, the German Society of Dermatology, the Board of German Dermatologists and the German Speaking Mycological Society. Mycoses. 2012;55 (Suppl 3):1-13.

Sobel JD. Vulvovaginal candidosis. Lancet. 2007;369(9577):1961-71.

Fardiazar Z, Ronaci F, Torab R, Goldust M. Vulvovaginitis candidiasis recurrence during pregnancy. Pak J Biol Sci. 2012;15(8):399-402.

Ilkit M, Guzel AB. The epidemiology, pathogenesis, and diagnosis of vulvovaginal candidosis: a mycological perspective. Crit Rev Microbiol. 2011;37(3):250-61.

Mazor M, Chaim W, Shinwell ES, Glezerman M. Asymptomatic amniotic fluid invasion with Candida albicans in preterm premature rupture of membranes. Implications for obstetric and neonatal management. Acta Obstet Gynecol Scand. 1993;72(1):52-4.

Morrison EA, Cushman LF. Prevention of preterm delivery. N Engl J Med. 2007;357(19):1979.

Singh SI. Treatment of vulvovaginal candidiasis. Clin. Rev. CPJ/RPC. 2014;136(9):26-30.

Sobel JD. Vaginitis the New England journal of medicine. 1997;(337):1896-903.

Sobel JD. Epidemiology and pathogenesis of recurrent vulvovaginal candidiasis. Am J Obstet Gynecol. 1985;152(7 Pt 2):924-35.

Nelson M, Wanjiru W. Prevalence of Vaginal Candidiasis and Determination of the Occurrence of Candida Species in Pregnant Women Attending the Antenatal Clinic of Thika District Hospital, Kenya. Open Journal of Medical Microbiology. 2013;3(4):264-72.

Kanagal DV, Vineeth VK, Kundapur R, Shetty H, Rajesh A. Prevalence of Vaginal Candidiasis in Pregnancy among Coastal South Indian Women. J Womens Health, Issues Care. 2014;3:6.

Sparks RA, Williams GL, Boyce JM. Antenatal screening for candidiasis, trichomoniasis, and gonorrhoea. Br J Vener Dis. 1975;51(2):110-15.

Aslam M, Hafeez R, Ijaz S, Tahir M. Vulvovaginal Candidiasis in Pregnancy. Biomedica. 2008;24:54-6.

Parveen N, Munir AA. Frequency of vaginal candidiasis in pregnant women attending routine antenatal. clinic. J Coll Physicians Surg Pak. 2008;18(3).

Oyewole O, Okoliegbe IN. Prevalence of vaginal candidiasis among pregnant women attending Federal University of Technology, Minna, Nigeria, Bosso Clinic. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2013;4(1):113-20.

Yadav K, Prakash S. Prevalence of vulvovaginal candidiasis in pregnancy. Global Journal of Medicine and Medical Sciences. 2016;4(1):108-16.

Nurat AA, Babalola GO, Shittu MO. Detection and Epidemiology of Vulvovaginal Candidiasis among Asymptomatic Pregnant Women Attending a Tertiary Hospital in Ogbomoso, Nigeria. International Journal of Biomedical Research. 2015;6(7).

Czeizel AE, Tóth M, Rockenbauer M. No teratogenic effect after clotrimazole therapy during pregnancy. Epidemiology. 1999;10(4):437-40.

Rosa FW, Baum C, Shaw M. Pregnancy outcomes after first-trimester vaginitis drug therapy. Obstet Gynecol. 1987;69(5):751-5.

Young GL, Jewell D. Topical treatment for vaginal candidiasis (thrush) in pregnancy. Cochrane Database Syst Rev. 2001;4:CD000225.