Is there any role of antibiotic as a post procedure prophylaxis in dilatation and curettage? A comparative single centre study at tertiary care centre
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20214637Keywords:
Antibiotic Resistance, Common Gynecology Procedure, Dilatation and curettageAbstract
Background: Dilatation and curettage (D and C) is one of commonest procedure in the gynaecology. There are still two schools of thoughts pertaining to whether to administer antibiotic as a pre and post procedure prophylaxis or not to administer and hence study planned to evaluate the incidence of infection in patients after dilation and curettage with and without prophylactic antibiotics.
Methods: Adults (>18 years) (n=100) who underwent dilatation and curettage procedure for any indication were included and patients with prior history of infection were excluded from the study. Patients were divided into 2 groups; group 1 (n=50) received prophylactic antibiotics and group 2 (n=50) received no prophylactic antibiotics as per the discretion of treating doctor.
Results: Infection in both the groups was 2% and there is no statistically significant difference between the groups (p>0.349).
Conclusions: Appropriate use of antibiotics can be a cost-effective strategy which can minimize the chances of development of antibiotic resistance and other side effects. Antibiotic are not necessary for pre and post procedure prophylaxis in D and C.
References
Cooper DB, Menefee GW. Dilation and Curettage. StatPearls [Internet]. 2021 Mar 21.
Cavaliere A, Ermito S, Dinatale A, Pedata R. Management of molar pregnancy. Journal of Prenatal Medicine. 2009;3(1):15.
MacKenzie IZ, Bibby JG. Critical assessment of dilatation and curettage in 1029 women. The Lancet. 1978;312(8089):566-8.
Amarin ZO, Badria LF. A survey of uterine perforation following dilatation and curettage or evacuation of retained products of conception. Archives of gynecology and obstetrics. 2005;271(3):203-6.
Grimes DA. Diagnostic dilation and curettage: a reappraisal. American journal of obstetrics and gynecology. 1982;142(1):1-6.
Weström L. Incidence, prevalence, and trends of acute pelvic inflammatory disease and its consequences in industrialized countries. Am J Obstet Gynecol. 1980;138;7(2):880-92
Low N, Mueller M, Van Vliet HA, Kapp N. Perioperative antibiotics to prevent infection after first‐trimester abortion. Cochrane Database of Systematic Reviews. 2012(3).
Thinkhamrop J, Laopaiboon M, Lumbiganon P. Prophylactic antibiotics for transcervical intrauterine procedures. Cochrane Database of Systematic Reviews. 2007(3).
Faro C, Faro S. Postoperative pelvic infections. Infectious disease clinics of North America. 2008 Dec 1;22(4):653-63.
Bang RA, Baitule M, Sarmukaddam S, Bang AT, Choudhary Y, Tale O. High prevalence of gynaecological diseases in rural Indian women. The Lancet. 1989;333(8629):85-8.
Rani B, Abhay B. Why women hide them, rural women’s viewpoint on reproductive tract infections. Haushi-a journal about women and society, New Delhi. 1992;69:27-30.
Prieto JA, Eriksen NL, Blanco JD. A randomized trial of prophylactic doxycycline for curettage in incomplete abortion. Obstetrics and Gynecology. 1995;85(5):692-6.
Makris N, Iatrakis G, Sakellaropoulos G, Rodolakis A, Michalas S. The role of antibiotics after dilatation and curettage in women with metrorrhagia in the prevention of pelvic inflammatory disease. Clinical and experimental Obstetrics and Gynecology. 2000;27(1):27-8.
Titapant V, Cherdchoogieat P. Effectiveness of cefoxitin on preventing endometritis after uterine curettage for spontaneous incomplete abortion: a randomized controlled trial study. Journal of the Medical Association of Thailand. 2012;95(11):1372.
Walling AD. Antibiotic prophylaxis for gynecologic procedures. American Family Physician. 2001;64(4):676.
Lushniak BD. Antibiotic resistance: a public health crisis. Public Health Reports. 2014;129(4):314-6.
