Concurrent cytologic and colposcopic evaluation of symptomatic cervical erosion

Authors

  • Shreya Goel Department of Obstetrics and Gynaecology, Lady Hardinge Medical College, Delhi, India
  • Prabha Lal Department of Obstetrics and Gynaecology, Lady Hardinge Medical College, Delhi, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20215088

Keywords:

Erosion, Cytology, Colposcopy, Malignancy

Abstract

Background: Cervical cancer is amongst the leading causes of deaths due to cancer in developing countries. Moreover, preinvasive lesions of the cervix have a long latency period for conversion into malignancy and are also detectable by screening techniques. Hence, colposcopy in addition to cytology should be carried out wherever facility is available to ensure early detection and timely management.

Methods: Simultaneous cytology and colposcopy was done for 80 women with symptomatic cervical erosion followed by a colposcopic directed biopsy in women with MRCI >3. Finally, correlation between cytology, colposcopy and histopathological results was done.

Results: 65/80 women were biopsied. 12/80 women had MRCI >6 amongst which 10/80 were confirmed to have a high grade lesion on histopathology. 13/80 had lesser abnormalities (ASCUS and LSIL) amongst which 3/80 had CIN1 on histopathology. Only 2/80 had HSIL on cytology as compared to 8/80 on histopathology that had CIN 2/3. Lastly, only 1/80 had SCC on cytology compared to 2/80 on histopathology. The sensitivity, specificity, PPV and NPV of cytology and colposcopy for diagnosing cervical dysplasia was 46.1%, 83.5%, 35.2%, 88.8% and 84.6%, 86.5%, 55%, 96.6% respectively making colposcopy a better screening tool than cytology for evaluating cervical malignancy.

Conclusions: Colposcopic examination should ideally be carried out in all women with symptomatic cervical erosion in addition to cytology. Moreover, suspicious areas should be biopsied even if cytology is normal to exclude malignancy.

 

Metrics

Metrics Loading ...

References

Bruni L, Barrionuevo-Rosas L, Albero G, Aldea M, Serrano B, Valencia S, Brotons M, Mena M, Cosano R, Muñoz J, Bosch FX. ICO information centre on HPV and cancer (HPV information centre). Human papillomavirus and related diseases in India. J Clin Epidemiol. 2015;72:12-23.

Burkett BJ, Peterson CM, Birch LM, Brennan C, Nuckols ML, Ward BE, Crum CP. The relationship between contraceptives, sexual practices, and cervical human papillomavirus infection among a college population. J Clin Epidemiol. 1992;45(11):1295-302.

Srivastava AN, Misra JS, Srivastava S, Das BC, Gupta S. Cervical cancer screening in rural India: Status & current concepts. Indian J Med Res. 2018; 148(6):687.

Sharma S, Saini M, Saini A, Bhalla AA. Colposcopic evaluation of patients with abnormal cervical cytology and its histopathological correlation: an original article. J Gynecol Obstet. 2014;18(1):1-8.

Pankaj S, Nazneen S, Kumari S, Kumari A, Kumari A, Kumari J, et al. Comparison of conventional Pap smear and liquid-based cytology: A study of cervical cancer screening at tertiary care center in Bihar. Indian J Cancer. 2018;55(1):80.

Paswan A. VIA (visual inspection with acetic acid) and VILI (visual inspection with lugol’s iodine) as an initial approach with colposcopy as a next screening tool with its positive predictive value in low socioeconomic patients. Int J Reprod Contracept Obstet Gynecol. 2017;7(1):210-4.

Bhalerao A, Kulkarni S, Ghike S, Kawathalkar JS. Correlation of pap smear, colposcopy and histopathology in women with unhealthy cervix. J South Asian Feder Obst Gynaecol. 2012;4(2):97-8.

Goldacre MJ, Loudon N, Watt B, Grant G, Loudon JD, McPherson K, Vessey MP. Epidemiology and clinical significance of cervical erosion in women attending a family planning clinic. Br Med J. 1978; 1(6115):748-50.

Garg R, Desai R. Cytologic and colposcopic evaluation of all symptomatic women at tertiary care centre. Int J Adv Med. 2017;4(3):799.

Papa Dasari, S Rajathi, Surendra V Kumar, Colposcopic evaluation of cervix with persistent inflammatory Pap smear: A prospective analytical study, cytojournal. 2010;7:16.

Barut MU, Kale A, Kuyumcuoğlu U, Bozkurt M, Ağaçayak E, Özekinci S, Gul T. Analysis of sensitivity, specificity, and positive and negative predictive values of smear and colposcopy in diagnosis of premalignant and malignant cervical lesions. Medical science monitor. Int Med J Experiment Clin Res. 2015;21:3860.

Joshi C, Kujur P, Thakur N. Correlation of Pap smear and colposcopy in relation to histopathological findings in detection of premalignant lesions of cervix in a tertiary care centre. Int J Sci Stud. 2015;3(8):55-60.

Ashmita D, Shakuntala PN, Rao SR. Comparison and correlation of PAP smear, colposcopy and histopathology in symptomatic women and suspicious looking cervix in a tertiary hospital care centre. Int J Health Sci Res. 2013;3(5):50-9.

Downloads

Published

2021-12-28

How to Cite

Goel, S., & Lal, P. (2021). Concurrent cytologic and colposcopic evaluation of symptomatic cervical erosion. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 11(1), 125–129. https://doi.org/10.18203/2320-1770.ijrcog20215088

Issue

Section

Original Research Articles