Study to assess sub-foveal choroidal thickness in patients of preeclampsia through spectral domain optical coherence tomography

Astha Lalwani; Priye Suman Rastogi; Rehana Najam; Ashish Chander

doi:10.18203/2320-1770.ijrcog20214827

Authors

Astha Lalwani Department of Obstetrics and Gynecology, Teerthanker Mahaveer Medical College, Moradabad, Uttar Pradesh, India
Priye Suman Rastogi Department of Ophthalmology, Teerthanker Mahaveer Medical College, Moradabad, Uttar Pradesh, India
Rehana Najam Department of Obstetrics and Gynecology, Teerthanker Mahaveer Medical College, Moradabad, Uttar Pradesh, India
Ashish Chander Department of Ophthalmology, Teerthanker Mahaveer Medical College, Moradabad, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20214827

Keywords:

SFCT, Preeclampsia, MAP, OCT

Abstract

Background: Aim of the study was to assess sub-foveal choroidal thickness (SFCT) in preeclamptic patients by SD ocular coherence tomography (SD-OCT) and correlate its changes with severity of preeclampsia.

Method: This case control, observational study, conducted in department of ophthalmology in association with department of obstetrics and gynaecology. The subjects were split into two groups: study and control. Study group was further divided in to 2 groups i.e., group A (Patients with preeclampsia) and group B (Pregnant females without preeclampsia). Control group (Group C) of non-pregnant females of similar age group. Total 100 patients were taken in each group. Subjects from both study and control groups were subjected to SD-OCT and mean choroidal thickness of both eyes was noted. Data was noted and comparison of 3 groups was done.

Results: Baseline characters viz, age, period of gestation, and parity was comparable among all the groups as p>0.05. Mean arterial pressure (MAP) was 102.72±9.81 and 84.56±7.83 in group A and B respectively with statistically significant difference as p<0.01. Following a post hoc analysis, it was discovered that the SFCT of the healthy pregnancy group did not differ substantially from that of the control group, however the SFCT of the pre-eclampsia group was significantly higher than that of the control and healthy pregnancy groups.

Conclusions: Pre-eclampsia causes a greater increase in sub-foveal choroidal thickness than normal pregnancy or non-pregnant women. It has the potential to be used as a predictor or marker of pre-eclampsia severity.

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Author Biography

Astha Lalwani, Department of Obstetrics and Gynecology, Teerthanker Mahaveer Medical College, Moradabad, Uttar Pradesh, India

Associate Professor

Dept Of Obstetrics and Gynecology

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