DOI: https://dx.doi.org/10.18203/2320-1770.ijrcog20215077
Published: 2021-12-28

Histopathological evaluation of endometrial tissue in patients of abnormal uterine bleeding

Zothansangi ., Vanremmawii ., Naveen P.

Abstract


Background: Abnormal uterine bleeding (AUB) is one of the commonest complaints in the gynecology OPD. It is also one of the most common reason for hysterectomy among Mizo women. Endometrial biopsy is a gold standard and first step for diagnosis of AUB in a low resource setting like the North-east states of India. The aim of the study was to evaluate the histopathology of endometrium for proper management of AUB cases.

Methods: This was a prospective study done to evaluate the histopathology of all the cases of AUB who attended gynaecology OPD, from the year 2018 to 2020. This study comprised of 668 AUB cases and material of the study was endometrial tissue of the cases of Abnormal uterine bleeding collected by dilatation and curettage, and sent for histopathological study to the department of pathology.

Results: Most of the abnormal uterine bleeding patients was in the age group of 40 to 49 years, and the most common histopathological finding was proliferative endometrium, 35.5% followed by disordered proliferation, 21%. 14 cases of carcinoma endometrium were found among the age group above 40 years.

Conclusions: The research evident that all the women above 40 years old need to undergo screening, keeping in mind the higher risk of carcinoma in the older age group of women.


Keywords


Abnormal uterine bleeding, Histopathology, Endometrial hyperplasia, Carcinoma

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References


Albers JR, Hull SK, Wesley RM. Abnormal uterine bleeding. Am Fam Physician. 2004;69(8):1915-26.

ESHRE Capri Workshop Group, Collins J, Crosignani PG. Endometrial bleeding. Hum Reprod Update. 2007;13(5):421-31.

Munro MG, Critchley HO, Broder MS, Fraser IS, FIGO Working Group on Menstrual Disorders. FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age. Int J Gynaecol Obstet. 2011;113(1):3-13.

Khan R, Sherwani RK, Rana S, Hakim S, Jairajpuri Z. Clinco-Pathological Patterns in Women with Dysfunctional Uterine Bleeding. Iran J Pathol. 2016;11(1):20-6.

Sreedhar VV, Jyothi Ch, Rao MN, Saijala V, Charan Paul MNP, Lakshmi GV. Study of Histopathological Pattern of Endometrium in abnormal uterine Bleeding-A study of 150 cases-A study of 150 cases. Saudi J Pathol Microbiol. 2017;2(4):137-42.

McCluggage WG. My approach to the interpretation of endometrial biopsies and curettings. J Clin Pathol. 2006;59(8):801-12.

Dahlenbug-Hellweg G. Histopathology of endometrium. New York, NY: Sptringer-verlag; 1993.

Sajitha K, Padma SK, Shetty KJ, Kishan HL, Perni HS, Hedge P. Study of histological patterns of endometrium in abnormal uterine bleeding. CHRISMEDL Health Res. 2014;1(2):76-81.

Doraiswami S, Johnson T, Rao S, Rajkumar A, Vijayaraghavan J, Panicker VK. Study of endometrial pathology in abnormal uterine bleeding. J Obstet Gynaecol India. 2011;61(4):426-30.

Livingstone M, Fraser IS. Mechanisms of abnormal uterine bleeding. Hum Reprod Update. 2002;8(1):60-7.

Devi LS. Singh MR, Singh LR, Debnath K. The histological and histochemical study of endometrium in Dysfunctional uterine bleeding. J Med Soc. 2012;26(3):167-70.

Vaidya S, Lakhey M, Vaidya S, Sharma PK, Hirachand S, Lama S. Histopathological pattern of abnormal uterine bleeding in endometrial biopsies. Nepal Med Coll J. 2013;15(1):74-7.

Smriti S, Dwivedi, Bajpai M, Bushan I, Satkiri A. Spectrum of endometrial lesion observed on HPE of endometrial samples in women with abnormal uterine bleeding. Int J Res Med Sci.2019;7(11):4124-8.

Mirza T, Akram S, Mirza A, Aziz S, Mirza T, Mustansar T. Histopathological pattern of abnormal bleeding in endometrial biopsies. J Basic applied Sci. 2012;8(1):114-7.

Vani BS, Vani R, Jijiya BP. Histopathological evaluation of endometrial biopsies and curetting’s in abnormal uterine bleeding. Tropical J Pathol Microbiol. 2019;5(4):190-7.