Histopathological evaluation of endometrial tissue in patients of abnormal uterine bleeding


  • Zothansangi . Department of Pathology, Zoram Medical College, Falkawn, Aizawl, Mizoram, India
  • Vanremmawii . Department of Obstetrics and Gynaecology, Zoram Medical College, Falkawn, Aizawl, Mizoram, India
  • Naveen P. Department of Physiology, All India Institute of Medical Sciences, Guwahati, Assam, India




Abnormal uterine bleeding, Histopathology, Endometrial hyperplasia, Carcinoma


Background: Abnormal uterine bleeding (AUB) is one of the commonest complaints in the gynecology OPD. It is also one of the most common reason for hysterectomy among Mizo women. Endometrial biopsy is a gold standard and first step for diagnosis of AUB in a low resource setting like the North-east states of India. The aim of the study was to evaluate the histopathology of endometrium for proper management of AUB cases.

Methods: This was a prospective study done to evaluate the histopathology of all the cases of AUB who attended gynaecology OPD, from the year 2018 to 2020. This study comprised of 668 AUB cases and material of the study was endometrial tissue of the cases of Abnormal uterine bleeding collected by dilatation and curettage, and sent for histopathological study to the department of pathology.

Results: Most of the abnormal uterine bleeding patients was in the age group of 40 to 49 years, and the most common histopathological finding was proliferative endometrium, 35.5% followed by disordered proliferation, 21%. 14 cases of carcinoma endometrium were found among the age group above 40 years.

Conclusions: The research evident that all the women above 40 years old need to undergo screening, keeping in mind the higher risk of carcinoma in the older age group of women.


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Original Research Articles