Mifepristone and misoprostol in pregnancy termination in hyperthyroid patients

Shyam Sunder Sud, Mini Bhatnagar, Nishi Sud

Abstract


Incidence of clinical hyperthyroidism in pregnant patients has been reported as 0.25-2.8%. They may be anxious and may not opt for surgical methods of medical termination. Medical termination of pregnancy by Mifepristone and Misoprostol is increasingly being used. We do not know the efficacy of this method in hyperthyroidism.


Keywords


Mifepristone, Misoprostol, Hyperthyroidism

Full Text:

PDF

References


Casey BM, Leveno KJ. Thyroid disease in pregnancy. Obstet Gynaecol. 2006;108:1283.

Necetibumus, Isikustamer. Thyroid disease in pregnancy. Pak J Med Sci. 2013;29(5):1187-92.

Buneuicius R, Velickience D, Prage AJ. Mood and anxiety disorder in women with treated hyperthyroidism. Jr Hosp Psychiatry. 2005:27(2):133-9.

Mestman JH. Hyperthyroidism in pregnancy. Clin Obstet Gynaecol. 1997:40(1):45-69.

Rijal B, Shretha R, Jha B. Association of thyroid dysfunction among infertile women. Nepal Med Coll J. 2011;13(4):247-9.

Thoai D. Ngo, Min Hae Park, Haleena Shakur. Comparative effectiveness, safety and acceptability of medical abortion at home and in clinic: a systematic review. Bull WHO. 2011;89:360-70.

Creinin MD, Fox MC, Tear S, Chen A, Study Trial Group. A randomized comparison of Misoprostol6-8 hours versus 24 hours after mifepristone for abortion. Obstet Gynaecol. 2004;103:851-9.

Shannon C, Wiebe E, Jacot F. Regimens of misoprostol with mifepristone for early medical abortion: a randomized trial. BJOG. 2006;113:621-8.

Akin A, Blum J, Ozalp S, Onderoglu L. Results and lessons learned from a small medical abortion clinical study in Turkey. Contraception. 2004;70:401-6.