Meckel-Gruber syndrome: about a case identified during deliver

Authors

  • Mouhamadou Wade Department of Gynocology-Obstétrics, Phillipe Maguilen Senghor Health Centre, Cheikh Anta DIOP University, Dakar, Senegal
  • Mamour Gueye Department of Gynocology-Obstétrics, Phillipe Maguilen Senghor Health Centre, Cheikh Anta DIOP University, Dakar, Senegal
  • Aissatou Mbodji Department of Gynocology-Obstétrics, Phillipe Maguilen Senghor Health Centre, Cheikh Anta DIOP University, Dakar, Senegal
  • Mame D. Ndiaye Department of Gynocology-Obstétrics, Phillipe Maguilen Senghor Health Centre, Cheikh Anta DIOP University, Dakar, Senegal
  • Mouhamed Sene Department of Gynocology-Obstétrics, Phillipe Maguilen Senghor Health Centre, Cheikh Anta DIOP University, Dakar, Senegal
  • Magatte Mbaye Department of Gynocology-Obstétrics, Phillipe Maguilen Senghor Health Centre, Cheikh Anta DIOP University, Dakar, Senegal

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20220581

Keywords:

Meckel-Gruber, Fetal malformations, Antenatal diagnosis, Genetic counselling

Abstract

Meckel-Gruber syndrome is an autosomal recessive disorder, usually lethal, most commonly characterised by the classic triad of polycystic kidneys, occipital encephalocele and polydactyly. Antenatal diagnosis can be made by ultrasound between 10 and 14 weeks of amenorrhoea. Recognition of this syndrome is important in order to establish the diagnosis and provide genetic counselling. Finally, well supervised termination of pregnancy should be the rule for lethal fetal malformations in order to relieve the psychological suffering of patients. However, in certain situations or working conditions, the diagnosis can be made late or even discovered during childbirth. We report a case of Meckel Gruber syndrome discovered at birth.

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Published

2022-02-25

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Section

Case Reports