An evaluation of etiology of recurrent pregnancy loss: prospective observational study
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20221271Keywords:
Recurrent pregnancy loss, Miscarriages, Habitual abortionAbstract
Background: Recurrent pregnancy loss (RPL) is a global issue, affecting 1-2% of fertile women. RPL can be explained as two or more pregnancy losses which are documented either by ultrasonography or histopathological examination. This study aimed to evaluate etiology of RPLs.
Methods: This prospective observational study was carried out in 40 women with history of RPL attending outpatient department (OPD) and inpatient department (IPD) of the department of obstetrics and gynaecology at the tertiary care centre of Dr. Vitthalrao Vikhe Patil Foundation’s (DVVPF’s) Medical College, Ahmednagar. The study was carried out from April 2020 to May 2021 in 40 women with history of RPL.
Results: RPL most commonly occurs due to unexplained causes, followed by endocrinal causes. It was found most commonly in 21-30 years age group.
Conclusions:
References
Silver RM, Warren JE. Preconception counselling for women with thrombophilia. Clin Obstet Gynecol. 2006;49(4):906-19.
American Society of Reproductive Medicine. Evaluation and treatment of recurrent pregnancy loss: a committee opinion. Fertil Steril. 2012;98:1103-11.
Regan L, Backos M, Rai R. The investigation and treatment of couples with Recurrent frist trimester abdomen second trimester miscarriage. RCOG. 2010;17.
Singh A, Kujur A, Rathore K. An evaluation of recurrent pregnancy loss. Int J Reprod Contracept Obstet Gynecol. 2017;6:1332-5.
Shetty MB, Malyala M, Swarup A, Pocha S, Pathadan DS, Raju A. Recurrent pregnancy loss: challenge to obstetricians. Int J Reprod Contracept Obstet Gynecol. 2017;6:3376-80.
Zheng D, Li C, Wu T, Tang K. Factors associated with spontaneous abortion: a cross-sectional study of Chinese populations. Reproductive Health. 2017;14(1):33.
Ali S, Majid S, Ali MN, Taing S, El-Serehy HA, Al-Misned FA. Evaluation of etiology and pregnancy outcome in recurrent miscarriage patients. Saudi J Biol Sci. 2020;27(10):2809-17.
Imam SN, Shamsi, MB, Kumar K, Deka D, Dada R. Idiopathic recurrent pregnancy loss: role of paternal factors; a pilot study. J Reprod Infertil. 2011;12(4):267.
Costa OLN, Santos EMF, Jesus VSD, Netto EM. Reproductive outcome in pregnant women with recurrent pregnancy loss. Revista Brasileria de Ginecologia e Obstetricia. 2015;37:578-84.
Eltayeb SM, Ambusaidi SK, Gowri V, Alghafri WM. Etiological profile of Omani women with recurrent pregnancy loss. Saudi Med J. 2014;35:757-60.
Pluchino N, Drakopoulos P, Wenger JM, Petignat P, Streuli I, Genazzani AR. Hormonal causes of recurrent pregnancy loss (RPL). Hormones. 2014;13(3):314-22.
Warren JE, Silver RM. Genetics of pregnancy loss. Clin Obstet Gynecol. 2008;51(1):84-95.
Medrano-Uribe FA, Enríquez-Pérez MM, Reyes-Muñoz E. Prevalence of uterine anatomical anomalies in mexican women with recurrent pregnancy loss (RPL). Gaceta medica de Mexico. 2016;152(2):163-6.
Lee RM, Silver RM. Recurrent pregnancy loss: summary and clinical recommendations. Semin Reprod Med. 2000;18(4):433-40.
