Study of relationship between maternal high body mass index and obstetrical outcome
Keywords:BMI, Pre-eclampsia, Abnormal weight gain, Cesarean, Perinatal outcome
Background: Evaluate the impact of higher body mass index (BMI) on the maternal and perinatal outcome in pregnancies complicated by obesity.
Methods: This is prospective cohort study conducted in obstetrics and gynaecology department. The 86 women with BMI>25 kg/m2 (cases) were compared with 90 women with BMI<25 kg/m2 (control) with regard to ante-natal complications, intervention in labour, maternal morbidity and neonatal outcome. Outcome of these variables in both groups were calculated statistically.
Results: Obese women were significantly more likely to have gestational hypertension (OR=5.14; p=0.023) preeclampsia (OR=2.72; p=0.0445), gestational diabetes (OR=5.78; p=0.0133), abnormal weight gain (p=0.0001), induced labour (OR=2.26; p=0.04), cesarean delivery (OR=3.09; p=0.001), wound infection (OR=2.59; p=0.01) and adverse neonatal outcome.
Conclusions: Obesity is an independent risk factor for adverse pregnancy outcomes and hence preventable steps should be taken for reducing the maternal and perinatal morbidity and mortality.
The Demographic and Health Surveys Program. India National Family Health Survey NFHS‐4 2015-16. 2016.
District fact Sheet. Ahmedabad. India National Family Health Survey NFHS‐4 2015-16. 2016.
Misra A, Chowbey P, Makkar BM. Con sensus statement for diagnosis of obesity, ab dominal obesity and the metabolic syndrome for Asian Indians and recommendations for physical activity, medical and surgical management. J Assoc Physicians India. 2009;57:163-70.
Bhattacharya S, Campbell DM, Liston W. effect of body mass index on pregnancy outcome in nulliparous women delivering singleton babies. BMC public health. 2007;7:168.
Misra A. We Need Ethnic-Specific Criteria for Classification of BMI. In: Medeiros-Neto G, Halpern A, Bouchrad C, eds. Progress in Obesity Research. London, UK: John Libbey Eurotext Ltd. 2003;547-53.
Ehrenthal DB, Jurkovitz C, Hoffman M, Jiang X, Weintraub WS. Prepregnancy body mass index as an independent risk factor for pregnancy-induced hypertension. J Womens Health (Larchmt). 2011;20(1):67-72.
Susan Y, Callaghan WM, Kim SY, Schmid CH, Lau J, England LJ et al. Maternal obesity and risk of gestational diabetes mellitus. Diabetes care vol. 2007;30(8):P2070-6.
Faucher MA, Barger MK. A systematic review on GWG in obese women by class of obesity and maternal neonatal outcome. Women and birth. 2015;28(3):e70-9.
Wolfe KB, Rossi RA, Warshak CR. The effect of maternal obesity on the rate of failed induction of labor. Am J Obstet Gynecol. 2011;205:128.
Weiss JL, Malon FD, Emig D. Obesity, obstetric complications and cesarean delivery rate-a population-based screening study. FASTER Research Consortium. Am J Obstet Gynecol. 2004;190:1091.
Bhattacharya S, Campbell DM, Liston WA, Bhattacharya S. Effect of Body Mass Index on pregnancy outcomes in nulliparous women delivering singleton babies. BMC Public Health. 2007;7:168.
Pevzner L, Powers BL, Rayburn WF, Rumney P, Wing DA. Effects of maternal obesity on duration and outcomes of prostaglandin cervical ripening and labor induction. Obstet Gynecol. 2009;114(6):1315-2.
Cedergren MI. Maternal morbid obesity and the risk of adverse pregnancy outcome. Obstet Gynecol. 2004;103(2):219-24.
Denison FC, Price J, Graham C, Wild S, Liston 8: W. Maternal obesity, length of gestation, risk of postdates pregnancy and spontaneous onset of labour at term. BJOG. 2008;115:720-5.
Baeten JM, Bukusi EA, Lambe M. Pregnancy complications and outcomes among overweight and obese nulliparous women. Am J Pub Health. 2001;91:436-40.
Sebire NJ, Jolly M, Harris JP. Maternal obesity and pregnancy outcome a study of 287, 213 pregnancies in London. Int J. Obes Relat Metab Dis. 2001;25:1175-82.
Gaudet L, Ferraro ZM, Shi WW, Walker M. Maternal obesity and occurrence of fetal macrosomia: a systematic review and meta-analysis. Biomed Res Int. 2014;640291:22.
Minsart AF, Buekens P, De Spiegelaere M, Englert Y. License biomed central ltd. 2013-BMC pregnancy and Childbirth. 2013;13:36.
Kliegman RM, Gross T. perinatal problems of the obese mother and her infant. Obstet gynecol. 1985;66(3):299-306.