DOI: https://dx.doi.org/10.18203/2320-1770.ijrcog20220902
Published: 2022-03-25

Effect of bilateral salpingectomy with hysterectomy on ovarian reserve

Shakun Singh, Rudavath Bhavana, Rachna Chaudhary, Vandana Dhama

Abstract


Background: Aim of the study was to evaluate the effect of salpingectomy with hysterectomy on ovarian reserve.

Methods: This prospective case control study was done in the department of obstetrics and gynaecology from June 2020 to May 2021 on patients who underwent hysterectomy with or without salpingectomy were included in the study. Patients then divided into two groups of 30 in each group. In group A hysterectomy without salpingectomy were included. In group-B patients who underwent hysterectomy with salpingectomy were included, and then both groups were followed through Si-anti-Mullerian hormone (AMH), luteinizing hormone (LH), follicle stimulating hormone (FSH) and ovarian volume.

Results: Baseline AMH levels were 1.20 ng/mL for group-A, 1.29 ng/mL for group-B with no statistical significance. It was seen that AMH levels for across the group but of no statistical significance at any given follow up-line point. Baseline LH levels were 7.22 IU/L and 7.27 IU/L for group-A and group-B patients respectively with no statistical significance. The average LH levels seen to increase in the follow up period in both groups, but it was of no statistic significant at any given follow up time point. Baseline FSH levels were 7.58 IU/L and 6.84IU/L for group A and group-B respectively with no statistical significance. The average FSH levels were seen to increase is the follow up period in both groups.

Conclusions: The hysterectomy coupled with bilateral salpingectomy (BS) had minimal or no statistically significant impact on the ovarian reserve. Depends on patients’ profile and states of fallopian tube we should take decision of salpingectomy during surgery.


Keywords


Ovarian reserve, Hysterectomy, Salpingectomy

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References


Dutta DK, Dutta I. Abdominal Hysterectomy: A New Approach for Conventional Procedure. J Clin Diagn Res. 2014;8(4):OC15-8.

Siddiqui N, Pitkin J. Menstrual disturbances. Obstetr Gynaecol Reprod Med. 2007;17(5):154-62.

Robert F Casper, Robert L Barbieri, William F Crowley, Jr, Kathryn A Martin. Clinical manifestations and diagnosis of menopause. 2021.

Stricker R, Eberhart R, Chevailler MC, Quinn FA, Bischof P, Stricker R. Establishment of detailed reference values for luteinizing hormone, follicle stimulating hormone, oestradiol, and progesterone during different phases of the menstrual cycle on the Abbott ARCHITECT analyzer. Clin Chem Lab Med. 2006;44(7):883-7.

Kwon JS. Ovarian cancer risk reduction through opportunistic salpingectomy. J Gynecol Oncol. 2015;26(2):83.

Kwon JS, McAlpine JN, Hanley GE, Finlayson SJ, Cohen T, Miller DM et al. Costs and benefits of opportunistic salpingectomy as an ovarian cancer prevention strategy. Obstet Gynecol. 2015;125(2):338-45.

Minig L, Chuang L, Patrono MG, Cardenas-Rebollo JM, Garcia-Donas J. Surgical outcomes, and complications of prophylactic salpingectomy at the time of benign hysterectomy in premenopausal women. J Minim Invasive Gynecol. 2015;22(4):653-7.

Mummert T, Gnugnoli DM. Ectopic Pregnancy. StatPearls Publishing. 2022

Minig L, Chuang L, Patrono MG, Cardenas-Rebollo JM, Garcia-Donas. Surgical outcomes and complications of prophylactic salpingectomy at the time of benign hysterectomy in premenopausal women. J Minim Invasive Gynecol. 2015;22(4):653-7.

Yuan Z, Cao D, Bi X, Yu M, Yang J, Shen K. The effects of hysterectomy with bilateral salpingectomy on ovarian reserve. Int J Gynaecol Obstet. 2019;145(2):233-8.

Elmantwe AN, Elnory MA. Impact of prophylactic bilateral salpingectomy on ovarian reserve in women undergoing vaginal hysterectomy: A randomized controlled trial. EBWHJ. 2020;10(2):150-61.

Tehranian A, Zangbar RH, Aghajani F, Sepidarkish M, Rafiei S, Esfidani T. Effects of salpingectomy during abdominal hysterectomy on ovarian reserve: a randomized controlled trial. Gynecol Surg. 2017;14(1):17.

Huang D, Zhu Y, Chen J, Zhang S. Effect of modified laparoscopic salpingectomy on ovarian reserve: Changes in the serum antimüllerian hormone levels. Laparoscopic Endoscopic Robotic Surg. 2019;2(1):8-11.

Asgari Z, Tehranian A, Rouholamin S, Hosseini R, Sepidarkish M, Rezainejad M. Comparing surgical outcome and ovarian reserve after laparoscopic hysterectomy between two methods of with and without prophylactic bilateral salpingectomy: A randomized controlled trial. J Can Res Ther. 2018;14:543-8.

Morelli M, Venturella R, Mocciaro R, Di Cello A, Rania E, Lico D et al. Prophylactic salpingectomy in premenopausal low-risk women for ovarian cancer: primum non nocere. Gynecol Oncol. 2013;129(3):448-51.

Song T, Lee SH, Kim WY, Heo EJ, Kim TJ. Opportunistic salpingectomy does not affect ovarian reserve or surgical outcomes in patients undergoing laparoscopic myomectomy. Gynecologic and obstetric investigation. 2017;82(5):468-74.