A study to determine association of ovarian morphology with endometrial morphology and postmenopausal bleeding conducted in a tertiary care hospital
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20221278Keywords:
Endometrium, Ovary, Hyperplasia, Stroma, Postmenopausal bleedingAbstract
Background: Postmenopausal ovaries are chiefly composed of stroma and continue to have potential for hormonal synthesis. Ovarian stromal hyperplasia and endometrial hyperplasia/cancer are often identified concurrently, suggesting that ovarian morphology may represent a marker of cancer risk among older women.
Methods: An observational analytical cross-sectional study was conducted. Morphology of endometrium and ovary was studied in the specimens of total abdominal hysterectomy with unilateral/bilateral salpingo-oopherectomy in females with postmenopausal bleeding.
Results: Forty two specimens of total abdominal hysterectomy with bilateral hysterectomy were studied. Age of patients ranged from 45 to 80 years. Majority of patients were in the age group 45-55 years. Average duration of menopause was 6.2 years ranging from 1.5years to 30 years. Most common endometrial pathology noted was proliferative endometrium (20, 47.6%) followed by primary endometrial malignancy and endometrial polyp (14.3%). Majority of the ovaries were unremarkable (35.8%). Most common change noted was stromal hyperplasia (31.4%).
Conclusions: The study did not find statistically significant association between stromal hyperplasia/large ovary and high risk endometrial pathology.
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