Maternal history and second trimester uterine artery Doppler in the assessment of risk for development of early and late onset pre-eclampsia and intra uterine growth restriction

Humera Noor; Mahapara Manzoor; Saima Sadiq; Naveed Shahzad

doi:10.18203/2320-1770.ijrcog20161327

Authors

Humera Noor Department of Obstetrics and Gynaecology, Government Medical College, Srinagar, India
Mahapara Manzoor Department of Obstetrics and Gynaecology, Government Medical College, Srinagar, India
Saima Sadiq Department of Obstetrics and Gynaecology, Government Medical College, Srinagar, India
Naveed Shahzad Department of Health and Medical Education, Kashmir, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20161327

Keywords:

Pregnancy, Primigravida, Pre-eclampsia, Doppler, IUGR

Abstract

Background: To evaluate the value of one step uterine artery Doppler and maternal history in the prediction of early onset pre-eclampsia and intra uterine growth restriction in a random population

Methods: This study was conducted from 2012 to 2014 Lalla Ded hospital which is a tertiary care hospital associated with GMC Srinagar. This was a prospective study conducted on 200 pregnant women in the second trimester between 19-22 weeks of gestation. Singleton pregnant women were recruited from those attending antenatal care clinics at this hospital over a period of two years. Obstetric and medical history was taken. Transabdominal ultrasound was done and then patients were subjected to Doppler examination of uterine arteries.

Results: Mean age of study population was 26.3 years with maximum number of patients in 25-29 year age group. Total numbers of primigravida were 59.5%. Maternal history revealed that 9.5% had previous history of hypertensive pregnancy, 3.5% had history of IUGR. Early onset pre-eclampsia (<32 weeks) was present in 42.9% and late onset pre-eclampsia (>32 weeks) was present in 57.1% cases. Doppler abnormalities were present in 7.5%. In the patients who developed pre-eclampsia 57.1% had uterine artery Doppler abnormalities.

Conclusions: Maternal history and uterine artery Doppler at 19-22 weeks gestation is a single step test for the prediction of early onset(<32 weeks) and late onset pre-eclampsia and intra uterine growth restriction.

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