Clinical study of feto-maternal outcomes in cases of gestational diabetes mellitus


  • Jalpa K. Rathod Department of Obstetrics and Gynecology, B. J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India
  • Hafsa M. Vohra Department of Obstetrics and Gynecology, B. J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India
  • Jagruti V. Vasava Department of Obstetrics and Gynecology, B. J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India



Gestational diabetes mellitus, Demographic parameters, Glycemic control, Maternal and fetal complications associated with gestational diabetes mellitus


Background: To study of prevalence of gestational diabetes mellitus in the community, demographic parameters like age, gestational age at diagnosis, parity, complications related to gestational diabetes mellitus, and plan the management of gestational diabetes mellitus and to reduce the maternal and perinatal morbidity and mortality.

Methods: In this prospective observational study we included 50 patients with gestational diabetes mellitus were studied for feto-maternal outcome. The study was conducted from October 2018 to October 2020 at department of Obstetrics & Gynaecology, B. J. Medical college and Civil Hospital, Ahmedabad.

Results: Total 50 cases of gestational diabetes mellitus were studied. It was observed that gestational diabetes mellitus were more common in elderly age group (60%), multigravida patients wer more commonly involved (48%). Past history of gestational diabetes melllitus was present in 42.2% of cases, 74% of cases required insulin for glycemic control,64% cases required delivery by caesarean section, maternal complications like preeclampsia (10 cases), polyhydramnios (22), uteroplacental insufficiency (4), macrosomia, sudden intrauterine death (3) and operative delivery were more common. 6 neonates developed respiratory distress syndrome, 10 developed hypoglycemia, and 13 neonates required NICU admission, 6 neonates underwent perinatal mortality.

Conclusions: Gestational diabetes mellitus has become a global public health burden. Gestational Diabetes Mellitus is one of the leading causes of morbidity and mortality for both mother and infant worldwide. Early detection of gestational diabetes mellitus, timely referral, frequent antenatal visits, management of the identified cases at tertiary centres can lead to decreased maternal and fetal morbidity and mortality.


American diabetes association standards of medical care in diabetes-2010. Diab care. 2010;33:S11-6.

Metzger BE, Gabbe SG, Persson B, Buchanan TA, Catalano PA, Damm P, et al. International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy. Diabetes Care. 2010; 33(3):676-82.

Al-Rowaily MA, Abolfotouh MA. Predictors of gestational diabetes mellitus in a high-parity community in Saudi Arabia. East Mediterr Health J. 2010;16(6):636-41.

Thomas B. The prevelance, risk factors, maternal and fetal outcomes in in gestational diabetes mellitus. Int J Drug Develop Res. 2012; 4(3):356-68.

Jindal A. Prevalence, clinical profile and outcome of gestational diabetes mellitus. J Obstet Gynaecol. 2001; 51:46-8.

Saxena P, Tyagi S, Prakash A, Nigam A, Trivedi SS. Pregnancy outcome of women with gestational diabetes in a tertiary level hospital of north India. Indian J Commu Med. 2011;36(2):120-3.

Bellamy L, Casas JP, Ingrain AD. Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis. Lancet. 2009;373:1773-9.

Williams JW, Cunningham FG, Leveno KJ, Bloom SL, Spong CY, Dashe JS. Williams obstetrics. 25th ed. New York: McGrowHill; 2018:1107.

Tufnell DJ, West J, Walkinshaw SA. Treatments for gestational diabetes and impaired glucose tolerance in pregnancy.Int JDrug Develop Res. 2012;4(3):356-68.

NICE 2020 guidelines Diabetes in pregnancy: management from preconception to the postnatal period.Available at: NG3. Accessed on 16 December 2020.

O'Sullivan JB, Mahan CM. Criteria for the oral glucose tolerance test in pregnancy. Diabetes. 1964;13:278-85.






Original Research Articles