Published: 2022-05-26

Nodule in mesosalphinx: a rare microscopic finding

Sunila Jain, Kavita Karmacharya


Ectopic adrenal cortical rests are uncommon in adults, particularly in females. Their occurrence in fallopian tubes or mesosalphinx is extremely rare. Herein, we report a rare occurance of ectopic adrenal cortical rests in mesosalphinx which was diagnosed on histopathological examination. To the best of our knowledge, there are less than five previously published cases at this rare location and the present report is the second case from India. A 46-year-old female who underwent hysterectomy for fibroids was incidentally detected with ectopic adrenal cortical rests in the mesosalphinx on histopathology. The present case is reported to increase the awareness of this unique finding at this rare location, its implications and histopathological diagnosis.



Ectopic, Adrenal cortical, Fallopian tube, Mesosalphinx

Full Text:



Tzigkalidis T, Skandalou E, Manthou ME, Kolovogiannis N, Meditskou S. Adrenal Cortical Rests in the Fallopian Tube: Report of a Case and Review of the Literature. Medicines (Basel). 2021;8:14.

Tingi E, Ogah J. Ectopic adrenal rest cells of the fallopian tube: a case report and review of the literature. J Obstet Gynaecol. 2018;38:578-9.

Yousif MQ, Salih ZT, DeYoung BR, Qasem SA. Differentiating Intrarenal Ectopic Adrenal Tissue from Renal Cell Carcinoma in the Kidney. Int J Surg Pathol. 2018;26:588-92.

Falco EC, Daniele L, Metovic J, Bollito E, De Rosa G, Volante M et al. Adrenal Rests in the Uro-genital Tract of an Adult Population. Endocr Pathol. 2021;32:375-84.

Yokoyama H, Adachi T, Tsubouchi K, Tanaka M, Sasano H. Non-functioning adrenocortical carcinoma arising in an adrenal rest: immunohistochemical study of an adult patient. Tohoku J Exp Med. 2013;229:267-70.

Khandakar B, Dey S, Ray PS, Sarkar R, Bhattacharyya P. Ectopic Paratubal Adrenal Cell Rest Associated with Mucinous Cystadenoma of Ovary. J Clin Diagn Res. 2015;9:ED13-4.