Efficacy of Amla (Emblica officinanis) and Shibe yamani (potash alum) in the management of Candida vaginitis: a randomized standard controlled trial


  • Masuma Zaki Department of Ilmul Qabalat Wa Amraze Niswan, National Institute of Unani Medicine, Kottigepalya, Bengaluru-91, Karnataka, India
  • Wajeeha Begum Department of Ilmul Qabalat Wa Amraze Niswan, National Institute of Unani Medicine, Kottigepalya, Bengaluru-91, Karnataka, India
  • Mariyam Roqaiya Department of Ilmul Qabalat Wa Amraze Niswan, National Institute of Unani Medicine, Kottigepalya, Bengaluru-91, Karnataka, India




Candida vaginitis, Amla, Shibe yamani, Fluconazole, Vulvovaginal pruritus


Background: It has been estimated that 75% of all females experience at least one episode of Candida vaginitis with approximately 40-50% reporting a recurrence during their lifetime. The symptoms of vulvovaginal candidiasis are often painful and uncomfortable to the patient. The objective of this study was to assess the efficacy of Amla and Shibe yamani in the management of Candida vaginitis.

Methods: This randomized, single blind, standard controlled study was done to compare the efficacy of Amla and Shibe yamani against fluconazole and 2% miconazole on diagnosed subjects of Candida vaginitis. Test group (n=30) received Amla with honey orally and Shibe yamani intra-vaginally at bed time for 3 wks. Whereas control group received standard regime of single dose fluconazole 150 mg orally and 5g of miconazole 2% cream intravaginally for 7 days. The primary outcome measure was relief in the vulvovaginal pruritus (reduction in 5D itch score). Secondary outcome measures included change in wet mount and improvement in vaginal discharge.

Results: Vulvovaginal pruritus significantly decreased (P<0.001) after intervention in the two groups. Marked improvement was observed in vaginal discharge (P<0.001) in both the groups.70% of patients in test group and 80% in control group showed change in wet mount.

Conclusions: Test drugs provide statistically significant improvement in vulvovaginal pruritus, vaginal discharge and in wet mount test without any apparent side effects. It can serve as an alternative treatment for Candida vaginitis.


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