Effect of eclampsia on pregnancy outcome at the tertiary care center
Keywords:Eclampsia, Caesarean section, NICU, Prematurity
Background: Eclampsia is a common medical and life-threatening emergency condition mainly seen in 5-10% of all pregnancies and that is a major cause of maternal and perinatal morbidity and mortality The aim of the study to find out the fetomaternal outcomes of eclampsia in tertiary care hospital and to analyse the trend of eclampsia and associated epidemiological variables.
Methods: This retrospective analytical study was undertaken with 40 clinically diagnosed women with eclampsia in their third trimester of pregnancy in the Department of Obstetrics and Gynaecology, at tertiary care hospital from July 2020 to December 2021. Women who came to the hospital with eclampsia or developed eclampsia during hospital stay were included in our study.
Results: In our study, the antepartum eclampsia was in 32 cases (80%), primigravida 27 cases (67.5%), maternal age (21-30 years) 26 cases (65%). Cesarean section was the mode of delivery in 26 cases (65%). NICU admission is required by 20 neonates (50%).
Conclusions: Eclampsia is an important cause of maternal and perinatal morbidity and mortality. Providing quality antenatal health care services, increasing awareness of patients about warning symptoms, proper investigations, timely delivery, and proper monitoring in the intrapartum and postpartum period have the potential to improve maternal and perinatal outcomes.
Corton M, Leveno K, Bloom S, Dashe J, Spong C. Williams Obstetrics 24th Ed. McGraw Hill Education. 2014.
Sibai BM, Sarinoglu C, Mercer BM. Eclampsia: VII. Pregnancy outcome after eclampsia and long-term prognosis. Am J Obstet Gynecol. 1992;166(6):1757-63.
Roberts JM. Endothelial dysfunction in preeclampsia. Semin Reprod Endocrinol. 1998;16:5-15.
Kannar A, Patel M, Prajapati S, Chavda D. A retrospective study of 100 cases of Eclampsia: perinatal outcomes. Int J Reprod Contracept Obstet Gynecol. 2016;5:3898-901.
Akinola O, Fabamwo A, Gbadegesin A, Ottun A, Kusemiju O. Improving the clinical outcome in cases of eclampsia: the experience at Lagos State University Teaching Hospital, Ikeja. The Int J Third World Med. 2007;6:2.
Tukur J, Umar BA, Rabi RU. The pattern of eclampsia in a tertiary health facility situated in a semi-rural town in Northern Nigeria. Ann Afr Med. 2007;6(4):164-7.
Agarwal M, Gautam A. Study of fetomaternal outcome in eclampsia. Int J Reprod Contracept Obstet Gynecol 2020;9:4155-9.
Jain R, Bindal J. Maternal and perinatal outcomes in eclampsia: a retrospective analysis in a referral hospital. Int J Reprod Contracept Obstet Gynecol. 2017;6:2806-11
Agida TE, Adeka BI, Jibril KA. Pregnancy outcome in eclamptic at the university of Abuja teaching hospital, Gwagwalada, Abuja: a 3-year review. Nigerian J Clin Pract. 2010;13(4):394-8.
Douglas KA, Redman CW. Eclampsia in the United Kingdom. BMJ. 1994;309(6966):1395-400.
Abalos E, Cuesta C, Carroli G, Qureshi Z, Widmer M, Vogel JP, et al. Pre-eclampsia, eclampsia and adverse maternal and perinatal outcomes: a secondary analysis of the World Health Organization Multi-Country Survey on Maternal and Newborn Health. BJOG. 2014;121(1):14-24.