A rare case report of haemolytic uremic syndrome in post caesarean section
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20222495Keywords:
Haemolytic uremic syndrome, Postoperative oliguria, Microangiopathic haemolytic anemia and thrombocytopeniaAbstract
Haemolytic uremic syndrome (HUS) is a clinical syndrome characterised by progressive kidney failure associated with microangiopathic haemolytic anemia and thrombocytopenia. Women may be genetically predisposed to develop HUS which gets aggravated by pregnancy. We presented a case of 25 year old G2p1l1 with h/o 9 months amenorrhoea was admitted in active labour, underwent emergency caesarean section for non-progression of labour. Postoperatively patient had decreased urine output with unexplained thrombocytopenia with deranged renal function tests and increased serum LDH with normal coagulation profile and no any evidence of foci of infection for which HUS was suspected. Patient was treated with hemodialysis, plasmapheresis and other supportive medical treatment.
References
Saad AF, Roman J, Wyble A, Pacheco LD. Pregnancy-associated atypical hemolytic- uremic syndrome. Asia J Pharmaceut Report. 2016;6(1):125.
Sangani MA, Airao BB, Pandya MR. A rare case presentation of haemolytic uremic syndrome in post caesarean section. IJOGR. 2015;2(3):176-8.
Fakhouri F, Roumenina L, Provot F, Sallee M, Caillard S, Couzi L, et al. Pregnancy-associated haemolytic uremic syndrome revisited in the era of complement gene mutations. Am Soc Nephrol. 2010;21(5):859-67.
Khatod N, Mukharjee S, Malviya V. Postpartum atypical haemolytic uremic syndrome:a rare case report. Int J Reprod Contracept Obstet Gynecol. 2020;9(11):4710-2.
Siegler RL. Management of haemolytic-uremic syndrome. J Pediatr. 1988;112(6):1014-20.
