A lipid profile study in polycystic ovary syndrome women

Authors

  • Pooja Prajapati Department of Obstetrics and Gynaecology, Satguru Pratap Singh Hospital, Ludhiana, Punjab, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20223500

Keywords:

Polycystic ovaries syndrome, Lipid profile, BMI, HDL, LDL, VLDL, Cholesterol, Triglyceride

Abstract

Background: Dyslipidemia in PCOS has multifactorial causation and insulin resistance plays a pivotal role by stimulation of lipolysis and altered lipases which are characterized by higher triglyceride and lower high-density lipoprotein cholesterol.1

Methods: This observational cross-sectional study was conducted in the obstetrics and gynaecology department of SPS hospital Ludhiana Punjab and included 60 women with PCOS and 30 non PCOS women of age group 18-40 who meet the inclusion criteria.

Results: PCOS women with BMI <18.5 (underweight) their mean cholesterol, HDL, LDL, VLDL and triglycerides were 158.00, 48.00, 74.00, 35.60, 178.00 respectively. PCOS women with BMI ranging from >18.5-24.99 (normal) the mean±SD for cholesterol, HDL, LDL, VLDL and triglycerides were 169.50 ± 21.83, 44.86±2.66, 85.80±20.33, 38.84±3.57, 194.18±17.86 respectively. PCOS Subjects with BMI25-29.99 (overweight) Mean±SD for total cholesterol was 197.04±18.16, HDL=40.48±3.19, LDL=112.37±18.10, VLDL=44.20±2.89 and for triglycerides was 221.00±14.45.

Conclusions: An early treatment for obesity should be a priority to prevent cardiometabolic complications in future in women with Polycystic ovaries syndrome.

 

References

Lath R, Shendye R, Jibhkate A. Insulin resistance and lipid profile in polycystic ovary syndrome. Asian J Biomed Pharm Sci. 2015;5(48):30-5.

Cristian-Ioan I, Nicolae C, Dan M. Lipid parameters in patients with polycystic ovary syndrome. Appl Med Inform. 2012;31(4):27-32.

Kiranmayee D, Kavya K, Himabindu Y, Sriharibabu M, Madhuri GLJ, Venu S. Correlations between anthropometry and lipid profile in women with PCOS. J Hum Reprod Sci. 2017;10(3):167-72.

Pirwany IR, Fleming R, Greer IA, Packard CJ, Sattar N. Lipids and lipoprotein subfractions in women with PCOS: relationship to metabolic and endocrine parameters. Clin Endocrinol Oxf. 2001;54(4):447-53.

Valkenburg O, Steegers-Theunissen RPM, Smedts HPM, Dallinga-Thie GM, Fauser BCJM, Westerveld EH, et al. A More atherogenic serum lipoprotein profile is present in women with polycystic ovary syndrome: A case-control study. J Clin Endocrinol Metabol. 2007;93(2):470-6.

Berneis K, Rizzo M, Lazzaroni V, Fruzzetti F, Carmina E. Atherogenic lipoprotein phenotype and low-density lipoproteins size and subclasses in women with polycystic ovary syndrome. J Clin Endocrinol Metabol. 2007;92(1):186-9.

Macut D, Panidis D, Glick B, Spanos N, Petakov M, Beki J, et al. Lipid and lipoprotein profile in women with polycystic ovary syndrome. Can J Physiol Pharm. 2008;86(4):199-204.

Rocha MP, Marcondes JAM, Barcellos CRG, Hayashida SAY, Curi DDG, da Fonseca ÂM, et al. Dyslipidemia in women with polycystic ovary syndrome: incidence, pattern and predictors. Gynecol Endocrinol. 2011;27(10):814-9.

Sudha A. Study of insulin resistance and lipid profile in polycystic ovarian syndrome. Int J Sci Res Publ. 2016;6(2):2250-3153.

Saghafi-Asl M, Pirouzpanah S, Ebrahimi-Mameghani M, Asghari-Jafarabadi M, Aliashrafi S, et al. Lipid profile in relation to anthropometric indices and insulin resistance in overweight women with polycystic ovary syndrome. Health Promot Perspect. 2013;3(2):206-16.

lae C, Dan M. Lipid parameters in patients with polycystic ovary syndrome. Appl Med Inform. 2012;31(4):27-32.

Kiranmayee D, Kavya K, Himabindu Y, Sriharibabu M, Madhuri GLJ, Venu S. Correlations between anthropometry and lipid profile in women with PCOS. J Hum Reprod Sci. 2017;10(3):167-72.

Pirwany IR, Fleming R, Greer IA, Packard CJ, Sattar N. Lipids and lipoprotein subfractions in women with PCOS: relationship to metabolic and endocrine parameters. Clin Endocrinol (Oxf). 2001;54(4):447-53.

Valkenburg O, Steegers-Theunissen RPM, Smedts HPM, Dallinga-Thie G. M, Fauser BCJM, Westerveld EH, et al. A More atherogenic serum lipoprotein profile is present in women with polycystic ovary syndrome: A case-control study. J Clin Endocrinol Metabol. 2007;93(2):470-6.

Berneis K, Rizzo M, Lazzaroni V, Fruzzetti F, Carmina E. Atherogenic lipoprotein phenotype and low-density lipoproteins size and subclasses in women with polycystic ovary syndrome. J Clin Endocrinol Metabol. 2007;92(1):186-89.

Macut D, Panidis D, Glick B, Spanos N, Petakov M., Beki J, Damjanovic S. Lipid and lipoprotein profile in women with polycystic ovary syndrome. Can J Physiol Pharm 2008:86(4):199–204.

Rocha M P, Marcondes J A M, Barcellos C R G, Hayashida S A Y, Curi D D G, da Fonseca  M, Baracat E. C. Dyslipidemia in women with polycystic ovary syndrome: incidence, pattern and predictors. Gynecol Endocrinol. 2011;27(10):814-9.

Sudha A. Study of insulin resistance and lipid profile in polycystic ovarian syndrome. Int J Sci Res Publ. 2016;6(2):2250-3153.

Saghafi-Asl M, Pirouzpanah S, Ebrahimi-Mameghani M, Asghari-Jafarabadi M, Aliashrafi S, et al. Lipid profile in relation to anthropometric indices and insulin resistance in overweight women with polycystic ovary syndrome. Health Promot Perspect. 2013;3(2):206-16.

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Published

2022-12-28

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Original Research Articles