Effectiveness of mifepristone versus balloon catheter in induction of labour in women with previous caesarean sections: a randomised comparative study

Authors

  • Yugantika Tomar Department of Obstetrics and Gynaecology, Teerthankar Mahaveer Medical College, Moradabad, Uttar Pradesh, India http://orcid.org/0000-0002-0551-9077
  • Rehana Najam Department of Obstetrics and Gynaecology, Teerthankar Mahaveer Medical College, Moradabad, Uttar Pradesh, India
  • Mrinalini Singh Department of Obstetrics and Gynaecology, Teerthankar Mahaveer Medical College, Moradabad, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20223326

Keywords:

Bishops, Pregnancy, Caesarean, Mifepristone

Abstract

Background: Termination of pregnancy is a stressful situation for the patient specially due to increasing trend of caesarean sections (CS) wherein due to risk of scar rupture a repeat caesarean is advocated by many practitioners. Especially in these cases vaginal delivery should be preferred over CS to avoid the added stress of a major surgery to the woman which increases the risk of scar rupture and adhesions in subsequent pregnancies. Hence the aim was to compare the safety and effectiveness of mifepristone versus balloon catheter in termination of pregnancy in women with previous CS.

Methods: Prospective randomized comparative study was done at obstetrics and gynaecology department of Teerthankar Mahaveer medical college and research centre, Moradabad UP from January 2020 to July 2021. 60 subjects were randomised into 2 groups by the envelope method.

Results: The mean bishops score at 36 hours was found to be 10.2±1.25 and 9.81±1.54 in groups M and B respectively. No statistically significant difference was found between the bishops score of the two groups at 24 and 36 hours. Patients induced with mifepristone had significantly longer induction delivery, Induction augmentation and Induction-labour intervals. However, these patients ultimately had more number favourable outcomes in terms of vaginal delivery, although not statistically significant. 

Conclusions: Foleys insertion is an invasive and painful process and more uncomfortable for the patient. Mifepristone can safely be used in place of foleys catheter for induction of labour in patients with previous 1 CS.

Author Biographies

Yugantika Tomar, Department of Obstetrics and Gynaecology, Teerthankar Mahaveer Medical College, Moradabad, Uttar Pradesh, India

Department of Obstetrics and Gynaecology, Senior Resident

Rehana Najam, Department of Obstetrics and Gynaecology, Teerthankar Mahaveer Medical College, Moradabad, Uttar Pradesh, India

Professor and Head, Department of Obstetrics and Gynaecology

Mrinalini Singh, Department of Obstetrics and Gynaecology, Teerthankar Mahaveer Medical College, Moradabad, Uttar Pradesh, India

Junior Resident, Department of Obstetrics and Gynaecology

References

Souza J, Gulmezoglu AM, Lumbiganon P, Laopaiboon M, Carrin G, Fawole B et al. WHO Global Survey on Maternal and Perinatal Health. BMC Med. 2010;8(71):1-10.

Mozurkewich EL, Chilimigras JL, Berman DR, Perni UC, Romero VC, King VJ et al. Methods of induction of labour: A systematic review. BMC Pregnancy Childbirth. 2011;11.

Singh R, Pradeep Y. Maternal and neonatal outcomes in morbidly adherent placenta: a developing country experience. Tropical Doc. 2015;45(3):183-7.

Sharma C, Soni A, Gupta A, Verma A, Verma S. Mifepristone vs balloon catheter for labor induction in previous cesarean: a randomized controlled trial. Arch Gynecol Obstet. 2017;296(2):241-8.

Dahiya K, Yadav N, Dahiya P, Nandal I. Comparative study of mifepristone versus balloon catheter for cervical ripening and induction of labour in previous caesarean section. International J Reprod Contracept Obstet Gynecol. 2020;9(6):2504-8.

Prager M, Eneroth-Grimfors E, Edlund M, Marions L. A randomised controlled trial of intravaginal dinoprostone, intravaginal misoprostol and transcervical balloon catheter for labour induction. Int J Obstet Gynaecol. 2008;115(11):1443-50.

Stenlund PM, Ekman G, Aedo AR, Bygdeman M. Induction of labor with mifepristone: A randomized, double-blind study versus placebo. Acta Obstetricia et Gynecologica Scand. 1999;78(9):793-8.

Manish P, Rathore S, Benjamin SJ, Abraham A, Jeyaseelan V, Mathews JE. A randomised controlled trial comparing 30 mL and 80 mL in Foley catheter for induction of labour after the previous Caesarean section. Trop Doct. 2016;46(4):205-11.

Downloads

Published

2022-12-28

Issue

Section

Original Research Articles