Diprosopus tetraophthalmos: a rare congenital anomaly
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20230143Keywords:
Diprosopus, Tetraophthalmos, Conjoined twins, Craniofacial malformationAbstract
Diprosopus is an extremely rare form of conjoined twins which is found in newborns where there is partial or complete duplication of face. The etiology and pathophysiology remain unknown and no genetic mutations have definitively associated with the condition so far. This article described a case of an infant born at 33.4 weeks gestation with multiple congenital anomalies including diprosopus tetraophthalmos and discussed the possible hypothesis and implications of prenatal diagnosis.
References
Suryawanshi P, Deshpande M, Verma N, Mahendrakar V, Mahendrakar S. Craniofacial duplication: a case report. J Clin Diagn Res. 2013;7(9):2025-6.
Bidondo MP, Groisman B, Tardivo A, Tomasoni F, Tejeiro V, Camacho I, et al. Diprosopus: systematic review and report of two cases. Birth Defects Res Clin Mol Teratol. 2016;106(12):993-1007.
Olay M, Rojas J, Franco JA. Craniofacial duplication: one of the rarest malformations in humans. J Perinat Med. 2014;20(1):45-8.
Rabe SE. Diprosopus: a rare anomaly. Collective review and case report. Master of Medical Science in Plastic and Reconstructive Surgery. University of KwaZulu‐Natal; 2016.
Rabe SE, Daya M, Madaree A. Diprosopus: a review of the aetiology and case report of early surgery in a 7‐week‐old infant with partial facial duplication. Eur J Plast Surg. 2019;42(3):213‐22.
Mrinal B, Haque I. Diprosopus a rare craniofacial malformation. Asian J Neurosurg. 2018;13(4):1257-9.
D'Armiento M, Falleti J, Maruotti GM, Martinelli P. Diprosopus conjoined twins: radiologic, autoptic, and histologic study of a case. Fetal Pediatr Pathol. 2010;29(6):431-8.