Conservative management of a complex ovarian cyst in a case of Glanzmann’s thrombasthenia

Authors

  • Meena N. Satia Department of Obstetrics and Gynaecology, Seth G. S Medical College and KEM Hospital, Mumbai, Maharashtra, India
  • Madhavi Jandhyala Department of Obstetrics and Gynaecology, Seth G. S Medical College and KEM Hospital, Mumbai, Maharashtra, India
  • Vibha More Department of Obstetrics and Gynaecology, Seth G. S Medical College and KEM Hospital, Mumbai, Maharashtra, India
  • Chandrakala Shanmukhaiah Department of Clinical Haematology, Seth G. S Medical College and KEM Hospital, Mumbai, Maharashtra, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20161719

Keywords:

Glanzmann’s thrombasthenia, Complex ovarian cyst, Conservative management

Abstract

Complex ovarian cyst has many causes one of them being haemorrhagic cyst. Most of the haemorrhagic ovarian cyst present as an emergency, detailed clinical history is important before deciding the management. Reporting an interesting case of conservative management in a young patient of reproductive age group with variant Glanzmann’s Thrombasthenia which led to a very large ovarian haemorrhagic cyst and presented as a case of torsion of the ovarian cyst. This case highlights the importance of thorough history taking and evaluation prior to embarking on surgical interference in such cases of coagulation disorders. Glanzmann's thrombasthenia (GT) is a genetic disorder which is characterized by a defect in platelet aggregation resulting in bleeding due to absence or dysfunction of the platelet glycoprotein IIb/IIIa complex. It is a rare genetic disorder that follows autosomal recessive type of inheritance.

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References

Pittman MA Jr, Graham JB. Glanzmann's thrombopathy: an autosomal recessive trait in one family. Am J Med Sci. 1964;247:293-303.

Glanzmann E. Hereditaire Hamorrhagische thrombasthenic. Ein Beitrag Zur Pathologie der Blutplattchen. Jahrbuch Kinderheilkde. 1918;88:1-42.

Poon MC. Clinical use of recombinant human activated factor VII (rFVIIa) in the prevention and treatment of bleeding episodes in patients with Glanzmann’s thrombasthenia. Vasc Health Risk Manag. 2007;3:655-64.

George JN, Caen JP, Nurden AT. Glanzmann's thrombasthenia: the spectrum of clinical disease. Blood. 1990;75:1383-95.

Bisch FC, Bowen KJ, Hanson BS, Kudryk VL, Billman MA. Dental considerations for a Glanzmann’s thrombasthenia patient: case report. J Periodontol. 1996;67:536-40.

Fernandes Gomes M, de Melo RM, Plens G, Pontes EM, Silva MM, Da Rocha JC. Surgical and clinical management of a patient with Glanzmann’s thrombasthenia: a case report. Quintessence Int. 2004;35:617-20.

Sharp WJ, Khanduri UD, Christie BS. Rapid heterozygote detection in Glanzmann's thrombasthenia.Br J Haematol. 1998;101:66-9.

Kantarci A, Cebeci I, Firatli E, Atamer T, Tuncer O. Periodontal management of Glanzmann’s thrombasthenia: report of 3 cases. J Periodontol. 1996;67:816-20.

Franchini M, Zaffanello M, Veneri D. Recombinant factor VIIa. An update on its clinical use. Thromb Haemost. 2005;93:1027-35.

Yasemin I, Aysun K, Sibel K, Ismail S, Ali K. Intensive menstrual bleeding successfully treated with recombinant factor VIIa in Glanzmann's thrombasthenia. Clin Appl Thrombo Hemost. 2011;17:320-2.

Alatas E, Oztekin O, Hacioglu SK. Endometriosis in two sisters with Glanzmann's thrombasthenia. Fertil Steril. 2009;92:1496-8.

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Published

2017-01-05

How to Cite

Satia, M. N., Jandhyala, M., More, V., & Shanmukhaiah, C. (2017). Conservative management of a complex ovarian cyst in a case of Glanzmann’s thrombasthenia. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 5(6), 2052–2054. https://doi.org/10.18203/2320-1770.ijrcog20161719

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Section

Case Reports