The association of pre-pregnancy body mass index and risk of pre-eclampsia
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20230801Keywords:
Preeclampsia, BMI, Pre pregnancy weight, Gestational weight gainAbstract
Background: Preeclampsia is a pregnancy-related condition characterized by new-onset hypertension and proteinuria. Preeclampsia is responsible for 20% to 80% of mortality among pregnant in developing countries. Preeclampsia may cause prematurity and fetal growth restriction. It is the most serious complication affecting 2-8% of all pregnancies. The mortality and morbidity rates among the babies of pre-eclampsia mothers is five times higher than that among babies born to healthy mothers. Objective: To find the association between pre-pregnancy Body Mass Index (BMI) and gestational weight gain with incidence of pre-eclampsia.
Methods: Cross sectional Observational study was conducted among 140 cases. The study was conducted after obtaining approval from the ethics committee.
Results: In this study, in 27.9% of cases overweight, and in 12.1% of cases obesity were seen. In 60.7% of cases severe preeclampsia, and 39.3% of cases mild preeclampsia was reported. Preeclampsia had no significant association with age, marital life, parity, but had a significant association with liquor, birth weight, and NICU admission.
Conclusions: Pre pregnancy weight and Gestational weight gain were associated with high risk of preeclampsia.
References
Hutcheon JA, Lisonkova S, Joseph KS. Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy. Best Prac Res Clin Obstet Gynecol. 2011;25(4):391-403.
WHO, UNICEF, UNFPA, The World Bank. Trends in maternal mortality: 1990 to 2010. Geneva: World Health Organization; 2012
Duckitt K, Harrington D. Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies. BMJ. 2005;330:565.
Cnattingius S, Bergstrom R, Lipworth L, Kramer MS. Pre pregnancy weight and the risk of adverse pregnancy outcomes. N Engl J Med. 1998;338:147-52.
Thadhani R, Stampfer MJ, Hunter DJ, Manson JE, Solomon CG, Curhan GC. High body mass index and hypercholesterolemia: risk of hypertensive disorders of pregnancy. Obstet Gynecol. 1999;94:543-50.
Sebire NJ, Jolly M, Harris JP, Wadsworth J, Joffe M, Beard RW, et al. Maternal obesity and pregnancy outcome: a study of 287,213 pregnancies in London. Int J Obes Rel Metab Disord. 2001;25:1175-82.
Bodnar LM, Ness RB, Markovic N, Roberts JM. The risk of preeclampsia rises with increasing pre pregnancy body mass index. Ann Epidemiol. 2005;15:475-82.
Bhattacharya S, Campbell DM, Liston WA, Bhattacharya S. Effect of body mass index on pregnancy outcomes in nulliparous women delivering singleton babies. BMC Public Health. 2007;7:168.
Redman CW, Sargent IL. Latest advances in understanding preeclampsia. Science. 2005;308(5728):1592-4.
Xiao R, Sorensen TK, Williams MA, Luthy DA. Influence of pre-eclampsia on fetal growth. J Matern Fet Neonat Med. 2003;13(3):157-62.
Roberts JM, Pearson G, Cutler J, Lindheimer M. Pregnancy NWGoRoHD: summary of the NHLBI working group on research on hypertension during pregnancy. Hypertension. 2003;41(3):437-45.
Porreco RP, Barkey R. Peripartum intensive care. J Matern Fet Neonat Med. 2010;23(10):1136-8.
Irgens HU, Reisaeter L, Irgens LM, Lie RT. Long term mortality of mothers and fathers after preeclampsia population based cohort study. BMJ. 2001;323(7323):1213-7.
Haugen M, Brantsaeter AL, Winkvist A, Lissner L, Alexander J, Oftedal B, et al. Associations of pre-pregnancy body mass index and gestational weight gain with pregnancy outcome and postpartum weight retention: a prospective observational cohort study. Bmc Pregnancy and Childbirth. 2014;14.
Duley L. The global impact of pre-eclampsia and eclampsia. Semin Perinatol. 2009;33:130-7.
Shao Y, Qiu J, Huang H, Mao B, Dai W, Xiaochun He. Pre-pregnancy BMI, gestational weight gain and risk of preeclampsia: a birth cohort study in Lanzhou, China. BMC Pregnancy Childbirth. 2017;17:400:1-8
El-Makhzangy IM, Moeity F, Anwer MY. Relation between maternal obesity and increased risk of preeclampsia. Bull Alex Fac Med. 2010;46(2):207-19.
Wei YM, Yang HX, Zhu WW, Liu XY, Meng WY, Wang YQ, et al. Risk of adverse pregnancy outcomes stratified for pre-pregnancy body mass index. J Matern Fet Neonat Med. 2015:1-5.
Tsai IH, Chen CP, Sun FJ, Wu CH, Yeh SL. Associations of the pre-pregnancy body mass index and gestational weight gain with pregnancy outcomes in Taiwanese women. Asia Pac J Clin Nutr. 2012;21(1):82-7.
Liu X, Du J, Wang G, Chen Z, Wang W, Xi Q. Effect of pre-pregnancy body mass index on adverse pregnancy outcome in north of China. Arch Gynecol Obstet. 2011;283(1):65-70.
Chen Z, Du J, Shao L, Zheng L, Wu M, Ai M, ET AL. Prepregnancy body mass index, gestational weight gain, and pregnancy outcomes in China. Int J Gynaecol Obstet. 2010;109(1):41-4.
Baker AM, Haeri S. Estimating risk factors for development of preeclampsia in teen mothers. Arch Gynecol Obstet. 2012;286(5):1093-6.
Swank ML, Marshall NE, Caughey AB, Main EK, Gilbert WM, Melsop KA, et al. Pregnancy outcomes in the super obese, stratified by weight gain above and below Institute of Medicine Guidelines. Obstet Gynecol. 2014;124(6):1105-10.
Truong YN, Yee LM, Caughey AB, Cheng YW. Weight gain in pregnancy: does the Institute of Medicine have it right? Am J Obstet Gynecol. 2015;212(3):362.e1-8.
DeVader SR, Neeley HL, Myles TD, Leet TL. Evaluation of gestational weight gain guidelines for women with normal prepregnancy body mass index. Obstet Gynecol. 2007;110(4):745-51.
