Histopathological pattern of endometrial biopsy in abnormal uterine bleeding
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20230804Keywords:
Abnormal uterine bleeding, Endometrial biopsy, FIGO classification, HistopathologyAbstract
Background: Abnormal uterine bleeding is a common complaint in most women of different ages that prompts seeking gynaecologic care. This study aimed to determine the type of endometrial patterns of the different age categories of women who presented as a case of abnormal uterine bleeding.
Methods: This was a retrospective study conducted on 72 patients who were presented with abnormal uterine bleeding and had endometrial biopsy done in our hospital. The data on their age, presenting complaints, and comorbidities of all the women were collected. The patterns of endometrial changes were studied and classified in accordance to the FIGO classification.
Results: Seventy-two women with abnormal uterine bleeding demonstrated a fluctuating pattern of ten endometrial pathologies distributed among five age groups in the range of 31 to 65 years. Maximum number of cases of AUB were noted in the age group of (36-50) years (56 cases, 77.7%). Most common observed histopathological pattern in this study was normal cyclical patterns including proliferative endometrium (29.16%) and secretory endometrium (22.22%).
Conclusions: Histopathological examination of the endometrium shows a clear-cut differentiation between physiological and malignancy changes in the endometrium. Hence, endometrial sampling is considered the golden tool for accurate analysis of the endometrium.
References
Fraser IS, Critchley HO, Munro MG, Broder M. Can we achieve international agreement on terminologies and definitions used to describe abnormalities of menstrual bleeding? Hum Reprod. 2007;22(3):635-43.
Awwad JT, Toth TL. Schiff I. Abnormal uterine bleeding in the perimenopause. Int J Fertil Menopaus Stud. 1993;38(5):261-9.
Wren BG. Dysfunctional uterine bleeding. Aust Fam Phys. 1998;27(5):371-7.
Kafle N, Shaukin S, Kafle SU, Singh M, Parajuli SB. Histopathological pattern of endometrial biopsies in patients with abnormal uterine bleeding attending Birat Medical College Teaching Hospital. Birat J Health Sci. 2020;5(2):1035-9.
Kazemijaliseh H, Ramezani Tehrani F, Behboudi-Gandevani S, Khalili D, Hosseinpanah F, Azizi F. A population-based study of the prevalence of abnormal uterine bleeding and its related factors among iranian reproductive-age women: an updated data. Arch Iran Med. 2017;20(9):558-63.
ACOG Practice Bulletin: Clinical Management of Anovulatory Bleeding. Int J Gynaecol Obstet. 2001;72(3):263-71.
Clark TJ, Gupta JK. Endometrial sampling of gynaecological pathology. Obstet Gynaecol. 2002;4(3):169-74.
Munro MG, Critchley HOD, Fraser IS, Committee FMD. The two FIGO systems for normal and abnormal uterine bleeding symptoms and classification of causes of abnormal uterine bleeding in the reproductive years: 2018 revisions. Int J Gynecol Obstet. 2018;143(3):393-408.
Subhankar D, Barunoday C, Rejaul K, Ranen KA, Pradip KM, Tarun KG. Abnormal uterine bleeding in perimenopausal age: diagnostic options and accuracy. J Obstet Gynecol India. 2011;61(2):189-94
Revel A, Shushan A. Investigation of the infertile couple: hysteroscopy with endometrial biopsy is the gold standard investigation for abnormal uterine bleeding. Hum Reprod. 2002;17(8):1947-9.
