An intercomparison of maternal and neonatal outcomes between COVID-19 infected and non-infected antenatal patients

Sushila Kharakwal; Rajni Gautam; Prerana Mishra

doi:10.18203/2320-1770.ijrcog20231221

Authors

Sushila Kharakwal Department of Obstetrics and Gynaecology, Maharani Laxmi Bai Medical College, Jhansi, Uttar Pradesh, India
Rajni Gautam Department of Obstetrics and Gynaecology, Maharani Laxmi Bai Medical College, Jhansi, Uttar Pradesh, India
Prerana Mishra Department of Obstetrics and Gynaecology, Maharani Laxmi Bai Medical College, Jhansi, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20231221

Keywords:

Antenatal patients, COVID-19, Mortality and Morbidity Maternal and neonatal outcomes

Abstract

Background: Our study aimed to evaluate the severity of COVID-19 infection and pregnancy complications in pregnant women with and without COVID-19, and its impact on maternal and neonatal morbidity and mortality at a tertiary care hospital in India.

Methods: The research is a prospective, comparative, and observational study on antenatal patients with confirmed COVID-19 infection status.

Results: Results showed preterm labour was the most common maternal complication among COVID-19 infected pregnant women, leading to various complications and long-term developmental delays. Maternal mortality was significantly higher among COVID-19 positive patients compared to non-infected patients. Although neonatal mortality rates were not significantly impacted, morbidity in terms of preterm birth increased among neonates born to COVID-19 positive mothers, resulting in complications like respiratory distress syndrome, intraventricular haemorrhage, and sepsis.

Conclusions: our study found increased overall mortality in antenatal patients infected with COVID-19 compared to non-infected patients, consistent with previous studies. The increased mortality rates may be attributed to severe respiratory complications and co-morbidities associated with COVID-19 infection in pregnant women.

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