A retrospective study on ectopic pregnancy aspiration by transvaginal ultrasound at Institute of Kidney Diseases And Research Centre

Authors

  • Vineet V. Mishra Department of Obstetrics and Gynecology, Institute of Kidney Diseases and Research Centre, Asarwa, Ahmedabad, Gujarat, India
  • Priyanka Rane Department of Obstetrics and Gynecology, Institute of Kidney Diseases and Research Centre, Asarwa, Ahmedabad, Gujarat, India
  • Rohina S. Aggarwal Department of Obstetrics and Gynecology, Institute of Kidney Diseases and Research Centre, Asarwa, Ahmedabad, Gujarat, India
  • Kunur N. Shah Department of Obstetrics and Gynecology, Institute of Kidney Diseases and Research Centre, Asarwa, Ahmedabad, Gujarat, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20231541

Keywords:

Ectopic, Pregnancy, Transvaginal ultrasound guided aspiration

Abstract

Background: Majority of the reports suggest that the frequency of ectopic pregnancies have grown in the last 30 years, especially in patients conceived through artificial reproductive techniques (ART). To prevent severe morbidity and mortality its prompt diagnosis and appropriate management is important. In a select patient population, most of the unruptured, live ectopic pregnancies can be successfully managed without surgical intervention using trans-vaginal ultrasound guided aspiration and instillation of local injection KCl or administration of systemic Inj. Methotrexate.

Methods: This study is a hospital based retrospective cohort study from January 2014 to December 2022 on patients who presented to Institute of Kidney Diseases and Research Centre (IKDRC) with unruptured ectopic pregnancy confirmed with ultrasound and β HCG. All the patients were analyzed according to history, clinical presentation, investigations, treatment and complications.

Results: β-HCG day 1 or 2 post procedure dropped in all cases but in variable levels ranging from 1.3% to 85.88%, while the drop during days 7-10, was more significant and reassuring; ranged from 48.69% to 98.95%.

Conclusions: By aspiration of ectopic gestational sac transvaginally under ultrasonographic guidance it is able to preserve the integrity of uterus and fallopian tube and thus the future fertility. The study will educate other healthcare professionals.

 

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References

Ectopic pregnancy--United States, 1990-1992. Centers for Disease Control and Prevention (CDC).MMWR Morb Mortal Wkly Rep. 1995;44:46-8.

Barnhart KT, Sammel MD, Gracia CR, Chittams J,Hummel AC, Shaunik A. Risk factors for ectopic pregnancy in women with symptomatic first-trimester pregnancies. Fertil Steril. 2006;86:36-43.

Bouyer J, Coste J, Fernandez H, Pouly JL, Job-Spira N.Sites of ectopic pregnancy: a 10 year population-basedstudy of 1800 cases. Hum Reprod. 2002;17:3224-30.

Barrenetxea G, Barinaga-Rementeria L, Lopez de Larruzea A, Agirregoikoa JA, Mandiola M, Carbonero K. Heterotopic pregnancy: two cases and a comparative review. Fertil Steril. 2007;87:417.e915.

Maymon R, Shulman A. Controversies and problems in the current management of tubal pregnancy. Hum Reprod Update. 1996;2:541-51.

Rotas MA, Haberman S, Levgur M. Cesarean scar ectopic pregnancies: ectopic, diagnosis and management. Obstetrics Gynecology. 2006;107(6):1373-81.

Grimes HG, Nosal RA, Gallagher JC. Ovarian pregnancy: a series of 24 cases. Obstet Gynecol. 1983;61(2):174-180.

Ash A, Smith A, Maxwell D. Ceasarean scar pregnancy. BJOG: An International Journal of Obstetrics Gynaecology. 2007;114(3):253-63.

Rosen T. Placenta accrete and cesarean scar pregnancy: overlooked costs of the rising cesarean section rate. Clinics in perinatology. 2008;35(3):519-29.

Yu X, Zhang N, Zuo W. Cesarean scar pregnancy: an analysis of 100 cases. Zhonghua yi xue za zhi. 2008;35(3):519-29.

Shen L, Tan A, Zhu H, Guo C,Liu D, Huang W. Bilateral uterine artery chemoembolization with methotrexate for cesarean scar pregnancy. American Journal of Obstetrics and Gynecology. 2012;207(5):386, e1-e6.

Rotas MA, Haberman S, Levgur M. Cesarean scar ectopic pregnancies: etiology, diagnosis and management. Obstetrics Gynecology. 2006;107(6):1373-81.

Wu R, Klein MA, Mahboob S, Gupta M, Katz DS. Magnetic resonance imaging as an adjunct to ultrasound in evaluating cesarean scar ectopic pregnancy. Journal of Clinical Imaging Science. 2013;3.

Gaddagi RA, Chandrashekhar AP. A Clinical Study of Ectopic-pregnancy. Journal of Clinical Diagnostics Research. 2012;6:867-9.

Shetty S, Shetty A. A clinical study of Ectopic pregnancies in a Tertiary care hospital of Mangalore, India. Innovative Journal of Medical and Health Science. 2014;4(1):305-9.

Panchal D, Vasihanav G, Solanki K. Study of Management inpatient with Ectopic pregnancy. National journal of Integrated Research in Medicine. 2011;2(3):91-4.

Poonam Y, Uprety D, Banarjee B. Ectopic Pregnancy – two years review from BPKHIS, Nepal. Kathmandu Uni. Med J. 2005;3:365-9.

Sudha VS, Delphine RT. A retrospective study on ectopic pregnancy: a two year study. Int J Reprod Contracept Obstet Gynecol. 2016;5:4365-8.

Gupta R, Porwal S, Swamkar M, Sharma N, Maheshwari P. Incidence, trends and risk factors for ectopic pregnancies in a tertiary care hospital of Rajasthan. JPBMS. 2012;16(07).

Murray H, Baakdah H, Bardell T, Tuland T. Diagnosis and treatment of ectopic pregnancy. CMAJ. 2005;173(8):905-12.

Hwu YM, Hsu CY, Yang HY. Conservative treatment of caesarean scar pregnancy with transvaginal needle aspiration of the embryo. BJOG: An international Journal of Obstetrics Gynaecology. 2005;112(6):841-2.

Swenda TZ, Jogo AA. Ruptured tubal pregnancy in Makurid, North Central Nigaria. Niger J Med. 2008;17(1):75-7.

Mufti S, Rather S, Mufti S, Rangrez RA, Wasqa K. Ectopic pregnancy: an analysis of 114 cases. JK-Pract. 2012;17(4):20-3.

Bassam MA, Begam MA, Aswad AG, Jefout MA. Ultrasound guided Transvaginal Aspiration and Mechanical Destruction with local Methotrexate Injection is a promising Primary Treatment Approach for Caesarean Scar Ectopic Pregnancy (CSEP). Biomedical Pharmacology Journal. 2019;12(1):99-105.

Herman A, Weinraub Z, Avrech O, Maymon R, Ron-EI R, Bukovsky Y. Followup and outcome of isthmic pregnancy located in a previous cesarean section scar. Br J Obstet Gynacol. 1995;102:839-41.

Jurkovic D, Hillaby K, Woelfer B, Lawrence A, Salim R, Elson CJ. First trimester diagnosis and management of pregnancies implanted into the lower uterine segment cesarean section scar. Ultrasound Obstet Gynecol. 2003;21:220-7.

Godin PA, Bassil S, Donnez J. An ectopic pregnancy developing in a previous cesarean section scar. Fertil Steril. 1997;67:398-400.

Nawroth F, Foth D, Wilhelm L, Schmidt T, Warm M, Romer T. Conservative treatment of ectopic pregnancy in a cesearean section scar with methotrexate: A case report. Eur J Obstet Gynecol Reprod Biol. 2001;99:135.

Marcus SF, Macnamee M, Brinsden P. Heteroscopic pregnancyes after in vitro fertilization and embryo transfer. Hum Reprod. 1995;10:1232.

Clayton HB, Schieve LA, Peterson HB, Jameison DJ, Reynolds MA, Wright VC. A comparison of heterotopic and intrauterine only pregnancy outcomes after assisted reproductive technologies in the United States from 1999 to 2002. Fertil Steril 2007;87:303.

Verma U, Goharkhay N. Conservative management of cervical ectopic pregnteril. 2009;91:671.

Mansour RT, Aboulghar MA, Serour GI, Sattar MA, Kamal A, Amin YM. Multifetal pregnancy reduction: modification of the technique and analysis of the outcome. Fertil Steril. 1999;71:380-4.

Seow KM, Huang LW, Lin YH, Lin MYS, Tsai YL, Hwang JL. Cesarean scar pregnancy: issues in management. Ultrasound in Obstetrics and Gynecology. 2022;23(3):247-53.

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Published

2023-05-26

How to Cite

Mishra, V. V., Rane, P., Aggarwal, R. S., & Shah, K. N. (2023). A retrospective study on ectopic pregnancy aspiration by transvaginal ultrasound at Institute of Kidney Diseases And Research Centre. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 12(6), 1710–1715. https://doi.org/10.18203/2320-1770.ijrcog20231541

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Original Research Articles