Comparision of efficacy of visual inspection of cervix with acetic acid, Pap smear and colposcopy for prevention of cervical cancer
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20231542Keywords:
Cervical cancer, Colposcopy, Pap smear, Sensitivity, SpecificityAbstract
Background: Cervical cancer is second most common cancer in women globally. Overall 80% cases occurs in developing countries. An important reason for the high incidence of cervical cancer in developing countries is the lack of effective screening programs to detect precancerous conditions and treat before it progresses to invasive cancer due to severe restrictions on the availability of infrastructure, resources and funding. Aim of this study was to compare the sensitivity, specificity, PPV, and NPV of VIA, Pap smear and colposcopy with colposcopic directed biopsy (as a gold standard).
Methods: This prospective analytical study was conducted on 200 women’s (age>19 years) with abnormal cervix in the Department Of Obstetrics and Gynaecology, Government Medical College Kota from 1 august 2020 to 31 July 2022 who fulfil the Inclusion criteria. All the Symptomatic patients with symptoms like vaginal discharge postcoital bleeding, itching, and other gynaecological problems along with asymptomatic patients with accidental finding of bad cervix (cervical erosion).
Results: Maximum cases had common complaint of discharge per vaginum (60.55%), followed by post coital bleeding (11.5%). VIA when compared with HPR, had sensitivity 94.85% and specificity 74.76% and corresponding PPV 78% and NPV 94%. Paps smear when compared with HPR, the sensitivity was 62.89% and specificity was 89.32% and corresponding PPV 84.72% and NPV 71.88%. Colposcopy when compared with Histopathological report, the sensitivity was 70% and specificity was 91.26% and corresponding PPV 88.3% and NPV 76.4%.
Conclusions: Best result for early detection of pre-invasive lesions could be with combined use of Pap smear, VIA, colposcopy and colposcopy guided biopsy rather than any individual diagnostic procedure. It will immensely reduce the morbidity and mortality.
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