Sad fetus syndrome: a rare case report

Authors

  • Mamatha K. Department of Obstetrics and Gynecology, Mysore Medical College and Research Institute, Mysore, Karnataka, India
  • Lekha Prakash Gawda Department of Obstetrics and Gynecology, Mysore Medical College and Research Institute, Mysore, Karnataka, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20231580

Keywords:

Molar pregnancy, GTD, Partial mole

Abstract

Gestational trophoblastic disease (GTD) is a condition that develops from abnormal proliferation of placental trophoblasts. A rare division of GTD is a partial mole with a co-existing live fetus-a condition also referred to as “sad fetus syndrome” We report a rare case of a 24-year-old, primigravida with 26 weeks of gestational age with single live intrauterine gestation coexisting with partial molar pregnancy who had a spontaneous preterm delivery at 27 weeks. The post-natal period was uneventful and patient was followed up till βhcg normalised. The diagnostic challenges and dilemma associated with the management of molar pregnancies with an apparently normal fetus, especially in the second trimester, remains challenging.

 

Metrics

Metrics Loading ...

References

Stevens FT, Katzorke N, Tempfer C, Kreimer U, Bizjak GI, Fleisch MC et al. Gestational Trophoblastic Disorders: An Update in 2015. Geburtshilfe Frauenheilkd. 2015;75(10):1043-50.

Block MF, Merrill JA. Hydatidiform mole with coexistent fetus. Obstet Gynecol. 1982;60:129-34 2.

Beischer NA. Hydatidiform mole with coexistent fetus. Aust NZ J Obstet Gynaecol. 1966:127-41.

Braga A, Mora P, De Melo AC, Nogueira-Rodrigues A, Amim-Junior J, Rezende-Filho J et al. Challenges in the diagnosis and treatment of gestational trophoblastic neoplasia worldwide. World J Clin Oncol. 2019;10(2):28-37.

Al-Mulhim AA. Hydatidiform mole: a study of 90 cases. J Family Community Med. 2000;7:57-61.

De Franciscis P, Schiattarella A, Labriola D. A partial molar pregnancy associated with a fetus with intrauterine growth restriction delivered at 31 weeks: a case report. J Med Case Rep. 2019;13:204.

Mangla M, Kaur H, Khoiwal K. Partial mole with coexistent live fetus: A systematic review of case reports. J Turk Ger Gynecol Assoc. 2022;23(2):83-94.

Benson CB, Genest DR, Bernstein MR. Sonographic appearance of first trimester complete hydatidiform moles. Ultrasound Obstet Gynecol. 2000;16:188-91.

Sebire NJ, Foskett M, Paradinas FJ, Fisher RA, Francis RJ, Short D et al. Outcome of pregnancies with complete hydatidiform mole and healthy co-twin. Lancet. 2002;359:2165-6.

Kim SJ, Bae SN, Kim JH, Han KT, Chung JK, Lee JM. Epidemiology and time trends of gestational trophoblastic disease in Korea. Int J Gyne Obst. 1998;60(1):S33-8.

Downloads

Published

2023-05-26

How to Cite

K., M., & Gawda, L. P. (2023). Sad fetus syndrome: a rare case report. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 12(6), 1905–1907. https://doi.org/10.18203/2320-1770.ijrcog20231580

Issue

Section

Case Reports