Fetomaternal outcome in pregnant women with derranged thyroid function
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20231556Keywords:
Hyperthyroidism, Hypothyroidism, Subclinical hypothyroidismAbstract
Background: Thyroid dysfunction is the second most common endocrine disorder observed during pregnancy after diabetes. Universal screening of thyroid disorders is recommended in the first trimester of pregnancy. The present study aims to determine the fetomaternal outcome in women with thyroid dysfunction.
Methods: The study was a prospective observational study conducted at Department of Obstetrics and Gynaecology, Hindu Rao Hospital and North DMC Medical College, Delhi from January 2019 to June 2022. It was approved by Institutional Ethics Committee. Pregnant women aged 18 to 40 years up to 20 weeks of gestational age with singleton pregnancy were included in this study. All the data was entered in pre designed proforma. The data analysis was done by statistical package for Social Sciences (SPSS) version 21.0.
Results: A total of 110 pregnant women were included in the study. 55 pregnant women with thyroid dysfunction were taken as study group and 55 euthyroid pregnant women were taken as controls. With respect to maternal complications, neonatal birth weight and Apgar score in the study group are significant.
Conclusions: Timely screening for thyroid dysfunction during pregnancy will reduce fetomaternal complications.
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References
Abalovich M, Amino N, Barbour LA, Cobin RH, De Groot LJ, Glinoer D, Mandel SJ, Stagnaro-Green A. Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metabol. 2007;92(8_supplement):s1-7.
Glinoer D. The systematic screening and management of hypothyroidism and hyperthyroidism during pregnancy. Trends in Endocrinol Metabol. 1998;9(10):403-11.
Gedam JK, Rajput DA. Prevalence of thyroid disorders among patients attending the antenatal clinic at tertiary care centre, Parel, Mumbai, India. Inter J of Reprod Contracep Obstet Gynecol. 2017;6(4):1235-9.
Marx H, Amin P, Lazarus JH. Hyperthyroidism and pregnancy. Bmj. 2008;336(7645):663-7.
Lazarus JH, Premawardhana LD. BEST PRACTICE NO 184 Screening for thyroid disease in pregnancy. J Clin Pathol. 2005;58(5):449-52.
Glinoer D, NAYER PD, Bourdoux P, Lemone M, Robyn C, Steirteghem AV, et al. Regulation of maternal thyroid during pregnancy. J Clin Endocrinol Metabol. 1990;71(2):276-87.
Hadley ME, Levine JE. Thyroid hormones. Endocrinol. 1996;4:290-337.
Casey BM, Leveno KJ. Thyroid disease in pregnancy. Obstet Gynaecol. 2006;108(5):1283-92.
Casey BM, Dashe JS, Wells CE, McIntire DD, Byrd W, Leveno KJ, Cunningham FG. Subclinical hypothyroidism and pregnancy outcomes. Obstet Gynecol. 2005;105(2):239-45.
Dussault JH, Fisher DA. Thyroid function in mothers of hypothyroid newborns. Obstet Gynecol. 1999;93(1):15-20.
Sreelatha S, Nadagoudar S, Asha Devi L. The study of maternal and fetal outcome in pregnant women with thyroid disorders. Int J Reprod Contracept Obstet Gynecol. 2017;6(8):3507-13.
Patel RD, Deliwala KJ, Shah PT, Singh RK, Fetomaternal outcome of thyroid disorder in pregnancy. Int J Reprod Conttacept Obstet Gynecol. 2016;5;4466-9.
Kumar R, Bansal R, Shergill HK, Garg P. Prevalence of thyroid dysfunction in pregnancy and its association with feto-maternal outcomes: A prospective observational study from a tertiary care institute in Northern India. Clin Epidemiol Glo Heal. 2023;19:101201.
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