Incidental finding of dysgerminoma in a full-term pregnancy: a case report


  • Isha A. Luniya Department of Obstetrics and Gynecology, Government medical college, Mira, Maharashtra, India
  • Vaibhav Patil Department of Obstetrics and Gynecology, Government medical college, Mira, Maharashtra, India
  • Nayana K. Department of Obstetrics and Gynecology, Government medical college, Mira, Maharashtra, India



Dysgerminoma, Ovarian tumor, Torsion, Peri-partum


Ovarian tumors are reported in 1 of every 200 pregnancies. Dysgerminoma with pregnancy is extremely rare, with a reported incidence of about 0.2-1 per 100,000 pregnancies. They are generally discovered due to their large size related complications like torsion, infarction, and obstruction of vaginal delivery. These rapidly growing tumors can have a heterogeneous presentation and lead to peripartum complications and morbidity. We present a unique case where a dysgerminoma went undiagnosed until labor in a patient who otherwise had an uncomplicated prenatal course. The purpose is to report and discuss our case, as further studies are needed to confirm the best management especially in the management of the incidentally diagnosed tumor.


Hyseni N, Llullaku S, Jashari H, Zahiti K, Hyseni F, Kurshumliu F et al. Advanced ovarian dysgerminoma infiltrating both ovaries and uterus in a 7-year-old girl. Case Rep Oncol Med. 2014;2014:910852.

Cheng L, Roth LM, Zhang S. KIT gene mutation and amplification in dysgerminoma of the ovary. Cancer. 2011;117(10):2096-103.

Biswajit D, Patil CN, Sagar TG. Clinical presentation and outcome of pediatric ovarian germ cell tumor: a study of 40 patients. J Pediatr Hematol-Oncol. 2010;32(2):e54-6.

Tangjitgamol S, Hanprasertpong J, Manusirivithaya S, Wootipoom V, Thavaramara T, Buhachat R. Malignant ovarian germ cell tumors: clinico-pathological presentation and survival outcomes. Acta Obstetricia et Gynecologica Scandinavica. 2010;89(2):182-9.

Kharane P, Tondage G, Munde S. Dysgerminoma with pregnancy and viable baby: A case report. MedPulse Int J Gynaecol. 2020;13(1):01-4.

Chen Y, Luo Y, Han C, Tian W, Yang W, Wang Y et al. Ovarian dysgerminoma in pregnancy: a case report and literature review. Cancer Biol Ther. 2018;19(8):649-58.

Gupta M, Saini V. Germ cell tumors and their association with pregnancy. Germ Cell. 2018;31:123.

Akhtar K, Ahmad SS, Kumar A, Afshan N. Dysgerminoma with pregnancy and viable baby: a case report. Oman Med J. 2011;26(3):198-200.

Zalel Y, Piura B, Elchalal U, Czernobilsky B, Antebi S, Dgani R. Diagnosis and management of malignant germ cell ovarian tumors in young females. Int J Gynaecol Obstet. 1996;55:1-10

De Palo G, Pilotti S, Kenda R, Ratti E, Musumeci R, Mangioni C et al. Natural history of dysgerminoma. Am J Obstet Gynecol. 1982;143(7):799-807.

Lee KH, Lee IH, Kim BG, Nam JH, Kim WK, Kang SB et al. Clinicopathologic characteristics of malignant germ cell tumors in the ovaries of Korean women. Kor Gynecologic Oncol Group Study. Int J Gynecol Cancer. 2009;19:84-7.

Gershenson DM. Update on malignant ovarian germ cell tumors. Cancer. 1993;71(4):1581-90.

Dgani R, Shoham Z, Atar E, Zosmer A, Lancet M. Ovarian carcinoma during pregnancy: a study of 23 cases in Israel between the years 1960 and 1984. Gynecol Oncol. 1989;33(3):326-31.

Tangir J, Zelterman D, Ma W, Schwartz PE. Reproductive function after conservative surgery and chemotherapy for malignant germ cell tumors of the ovary. Obstet Gynecol. 2003;101(2):251-7.

Kodama M, Grubbs BH, Blake EA, Cahoon SS, Murakami R, Kimura T et al. Feto-maternal outcomes of pregnancy complicated by ovarian malignant germ cell tumor: a systematic review of literature. Eur J Obstet Gynecol Reprod Biol. 2014;181:145-56.

Tewari K, Cappuccini F, Disaia PJ, Berman ML, Manetta A, Kohler MF. Malignant germ cell tumors of the ovary. Obstet Gynecol. 2000;95(1):128-33.

Quirk JT, Natarajan N. Ovarian cancer incidence in the United States, 1992-1999. Gynecol Oncol. 2005;97(2):519-23.

Williams SD, Blessing JA, DiSaia PJ. Second-look laparotomy in ovarian germ cell tumors: the gynecologic oncology group experience. Gynecol Oncol. 1994;52(3):287-91.






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