A comparison of buccal versus vaginal misoprostol administration for induction of first and second trimester abortion

Authors

  • Amita Yadav Department of Obstetrics and Gynaecology, Rani Durgavati Medical College, Banda, Uttar Pradesh, India
  • Nikita Kaushal Department of Obstetrics and Gynaecology, MLN Medical College, Prayagraj, Uttar Pradesh, India
  • Shubhangi Sonkar Department of Obstetrics and Gynaecology, MLN Medical College, Prayagraj, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20231765

Keywords:

Misoprostol, Abortion, First trimester, Second trimester

Abstract

Background: Aim of study was to compare effectiveness, adverse effects and patient’s acceptability of buccal and vaginal routes of administration of misoprostol in 1st and 2nd trimester abortion, type of study-randomized control trial

Methods: A total of 200 women with indications for abortion up to 20 weeks of pregnancy were enrolled over a period of 1 year and received misoprostol either through buccal (Group A) or vaginal (Group B) route. Each group containing 50 patients of first trimester and second trimester.

Results: Incomplete abortion rate (25%) was significantly higher in vaginal group while drug related side-effects (47%), patients’ satisfaction and acceptability (82%) was higher in buccal group respectively.

Conclusions: Buccal route may be preferred owing to a better complete abortion rate, better patient satisfaction and acceptability as compared to vaginal route.

References

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Published

2023-06-05

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Original Research Articles