A study on fetomaternal outcome of hypertensive disorders of pregnancy


  • Adarsh Preet Department of Obstetrics and Gynecology, Grant Government Medical College and JJ Group of Hospitals, Mumbai, Maharashtra, India
  • Ashok R. Anand Department of Obstetrics and Gynecology, Grant Government Medical College and JJ Group of Hospitals, Mumbai, Maharashtra, India




Blood pressure, Fetal outcome, Hypertensive disorders


Background: Hypertensive disorders of pregnancy are one of the most common medical disorders seen during pregnancy. Early diagnosis of hypertensive disorders in pregnancy by regular antenatal checkup can help in proper management, thus decreasing the maternal and fetal complications related it. Ensuring timely and effective care requires appropriate use of evidence-based clinical and nonclinical interventions, strengthened health infrastructure, and motivated and competent health care providers. The objective of this study was to study the feto-maternal outcome of hypertensive disorders of pregnancy and complications related to them.

Methods: A study was conducted in the department of obstetrics and gynecology at JJ Group of hospitals, Mumbai, India for a duration of 18 months from January 2020 to June 2021. This study had a sample size of 500 antenatal patients. Necessary information such as their detailed clinical, and obstetric history, clinical examination, investigations was noted.

Results: In our study, the incidence of hypertensive disorders of pregnancy was 10.2%, being most common in age group of 21-25 years (45.1%) and Primigravida patients (47.1%). The most common type of hypertensive disorder in our study was non severe preeclampsia with incidence of 74.50%. The most common complication was oligohydramnios (11.76%), followed by preterm delivery (9.80%) and IUGR (9.80%). The most common drug used in the management of hypertensive disorder was lobetalol. Most common neonatal complication in PIH group was low birth weight, followed by fetal distress (19.6%), prematurity (9.8%) and IUGR (9.8%).

Conclusions: Hypertensive disorders of pregnancy are one of the medical conditions affecting pregnancy. Hypertensive disorders of pregnancy are more prevalent in younger and nulliparous mothers. Early diagnosis and appropriate timely management of hypertensive disorders in pregnant women can prevent the maternal and fetal complications and improve the outcome of pregnancy. These women should be monitored carefully to prevent maternal morbidity and mortality.


James PR, Nelson-Piercy C. Management of hypertension before, during, and after pregnancy. Heart. 2004;90(12):1499-504.

Khan KS, Wojdyla D, Say L, Gülmezoglu AM, Van Look PF. WHO analysis of causes of maternal death: a systematic review. Lancet. 2006;367(9516):1066-74.

Creanga AA, Syverson C, Seed K, Callaghan WM. Pregnancy-related mortality in the United States, 2011-2013. Obstet Gynecol. 2017;130(2):366.

Berg CJ, Harper MA, Atkinson SM, Bell EA, Brown HL, Hage ML, et al. Preventability of pregnancy-related deaths: results of a state-wide review. Obstet Gynecol. 2005;106(6):1228-34.

Arias F, Bhide AG, Arulkumaran S, Damania K, Daftary SN, eds. Arias’ Practical guide to High-Risk Pregnancy and Delivery. 5th edn. Elsevier India; 2019:172.

National Institute of Health and Clinical excellence. Hypertension in pregnancy: The management of hypertensive disorders during pregnancy. CG no. 107. London, UK: National Institute of Health and Clinical excellence; 2010.

Milne F, Redman C, Walker J, Baker P, Bradley J, Cooper C, et al. The pre-eclampsia community guideline (PRECOG): how to screen for and detect onset of pre-eclampsia in the community. BMJ. 2005;330(7491):576-80.

WHO recommendations for prevention and treatment of pre-eclampsia and eclampsia. 2011. Available from: https://www.who.int/publications/ i/item/9789241548335. Accessed on 21 February 2023.

Sengodan SS, Sreeprathi N. Prevalence of hypertensive disorders of pregnancy and its maternal outcome in a tertiary care hospital, Salem, Tamil Nadu, India. Int J Reprod Contracept Obstet Gynecol. 2020;9:236-9.

Patel R, Baria H, Patel HR, Nayak S. A study on pregnancy induced hypertension and foetal outcome among patient with PIH at tertiary care hospital, Valsad. Int J Community Med Public Health. 2017;4(11):4277-81.

Gandhi MR, Jani PS, Patel UM, Kakani CR, Thakor NC, Gupta N. Perinatal outcome in pregnancy induced hypertension cases at GMERS Medical College, Dharpur-Patan, North Gujarat region, India: a prospective study. Int J Adv Med. 2015;2(2):152-5.

Parmar MT, Solanki HM, Gosalia VV. Study of risk factors of perinatal death in pregnancy induced hypertension. Nat J Community Med. 2012;3:703-7.

Jayaraman L, Khichi SK, Singh A, Goel S, Karkala J, Goyal P, et al. Pattern of feto-maternal outcome and complications in pregnancy induced hypertension from a tertiary level health care teaching institution of Tamil Nadu, India. Int J Res Med Sci. 2016;4:1402-6.

Liu CM, Cheng P, Chang SD. Maternal Complications and Perinatal Outcomes associated with Gestational Hypertension and Severe Preeclamsia in Taiwanese Women. J Formes Med Assoc. 2008;107(2):129-38.

Sajith M, Nimbargi V, Modi A, Sumariya R, Pawar A. Incidence of pregnancy induced hypertension and prescription pattern of antihypertensive drugs in pregnancy. Int J Pharm Sci Res. 2014;5(4):163-70.

Ramya C, Kumari R, Chitneni C. An observational study of early neonatal outcome in babies born to mothers with pregnancy induced hypertension. Int J Contemp Pediatr. 2020;7:1781-6.

Zafar H, Naz M, Fatima U, Irshad F. Frequency of IUGR in pregnancy induced hypertension. JUMDC. 2012;3(2):8-13.






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