Effect of anaemia on maternal and fetal outcome: an observational study
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20232719Keywords:
Anaemia, Postpartum haemorrhage, Shock, ICU admissionAbstract
Background: Anaemia in pregnancy is a globally health-related issue that affects both mothers and their new-born. Hence an observational study to see the effect of anaemia on maternal and foetal outcome was conducted.
Methods: 15024 mothers coming in OPD or IPD in past 4 years were recruited and their haemoglobin measured. Descriptive statistics was used for baseline characteristics. This observational study was conducted in department of obs and gynae, GSVM Medical College Kanpur from August 2018 to August 2022. All the data gathered was processed by SPSS version 25.
Results: The main outcomes included 4 maternal outcomes (postpartum haemorrhage, shock, ICU admission, and maternal mortality) and 4 neonatal outcomes (foetal growth restriction, birth weight, NICU admission, stillbirth). 60.03% of the mothers were anaemic in our study. Maternal and foetal complications were more in anaemic than non-anaemic mothers with incidence of PPH, shock, ICU admission, and maternal mortality being 14.07%, 11.33% ,4.30 and 1.31% respectively than non-anaemic mothers with incidence of 11.22%, 7.26%, 1.76%, and 7.28% respectively. Foetal outcome was also poorer in anaemic mothers with incidence of FGR, LBW, NICU admission, Still birth being 3.15%, 8.85%, 12.96%, and 1.09% higher than non-anaemic group with incidence being 1.80%, 3.43%, 9.75%, and 0.30 % respectively.
Conclusions: This observational study provides valuable insights into the effect of anaemia on both maternal and foetal outcomes. It emphasizes the importance of early detection and management of anaemia to mitigate the risks associated with this condition.
References
WHO Methods and Data Sources for Global Burden of Disease Estimates 2000-2011. Available at: https://cdn.who.int/media/docs/default-source/gho-documents/global-health-estimates/ghe2019_daly-methods.pdf. Accessed on 20 February 2023.
Prevalence of anemia in pregnant women. Available at: https://www.who.int/data/gho/data/themes/topics/anaemia_in_women_and_children. Accessed on 20 February 2023.
NFHS 5. Available at: https://anemiamuktbharat.info/. Accessed on 20 February 2023.
Health topics. Available at: https://www.who.int/ health-topics/anaemia. Accessed on 20 February 2023.
Goonewardene M, Shehata M, Hamad A. Anaemia in pregnancy. Best Pract Res Clin Obstetri Gynaecol. 2012;26(1):3-24.
Lee KA, Zaffke ME, Baratte-Beebe K. Restless legs syndrome and sleep disturbance during pregnancy: the role of folate and iron. J Womens Health Gend Based Med. 2004;10:335-41.
Murray-Kolb LE. Iron and brain functions. Curr Opin Clin Nutr Metab Care. 2013;16:703-7.
Beard J. Iron deficiency alters brain development and functioning. J Nutr. 2003;133:1468-72.
Milman N. Postpartum anemia II: prevention and treatment. Ann Hematol. 2012;91:143-54.
Bhutta ZA, Darmstadt GL, Hasan BS, Haws RA. Community-based interventions for improving perinatal and neonatal health outcomes in developing countries: A review of the evidence. Pediatrics. 2005; 115:519-617.
Gambling L, Danzeisen R, Fosset C, Andersen HS, Dunford S, Srai SKS, et al. Iron and copper interactions in development and the effect on pregnancy outcome, metal-binding proteins and trace element metabolism. J Nutr. 2003;133:1554-56.
Scholl TO, Johnson WG. Folic acid: influence on the outcome of pregnancy. Am J Clin Nutr. 2000;7:1295-303.
Hansda R, Tirkey S, Trivedi K, Singh P, Prakash J. Study on types of anaemia and foetomaternal outcome in antenatal patients. J Family Med Primary Care. 2022;11(6):3040.
Ghimire RH, Ghimire S. Maternal And Fetal Outcome Following Severe Anaemia In Pregnancy: Results From Nobel Medical College Teaching Hospital, Biratnagar, Nepal. J Nobel Med College. 2013;2(1):22-6.