Tobacco addiction and infertility in India: an overview

Garima Patel; Aryan Kashyap

doi:10.18203/2320-1770.ijrcog20232318

Authors

Garima Patel Department of Obstetrics and Gynecology, AIIMS, New Delhi, India
Aryan Kashyap Department of Obstetrics and Gynecology, AIIMS, New Delhi, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20232318

Keywords:

Tobacco, Smoking, Infertility

Abstract

Tobacco addiction is one of the oldest known addictions with annual death toll of three million. And India is the second largest consumer of tobacco in the world because of easy availability of variety of smoking and smokeless tobacco products in the market. This has made the situating very complex in India, as the same tobacco generating billions of revenues for India is also a financial burden over the health care sector. Tobacco is a risk factor for approximately 50 serious health care diseases including infertility. But it is surprising that only 22% of the general population are familiar with the reproductive risks associated with smoking. This shear ignorance has led to increase in smoking among women too. Tobacco use not only decrease fecundity and reproductive potential of the individual, but also causes relationship disharmony among the already emotional wrecked infertile couple. Though this stress might be the contributory factor towards tobacco abuse but ironically this tobacco use further escalates the financial ‘stress’ in these couples. Multiple attempts may be required during the process of quitting and the likelihood of success increases with each attempt. The ultimate key is counselling, education, and encouragement at each clinical visit.

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References

Peto R, Lopez AD, Boreham J, Thun M, Heath C Jr, Doll R. Mortality from smoking worldwide. Br Med Bull. 1996;52(1):12-21.

Jamal A, Phillips E, Gentzke AS, Homa DM, Babb SD, King BA, et al. Current Cigarette Smoking Among Adults - United States, 2016. MMWR Morb Mortal Wkly Rep. 2018;67(2):53-9.

NHS. What are the health risks of smoking?, 2018. Available at: https://www.nhs.uk/common-heahealthrisksofsmoking/. Accessed on 12 June 2023.

Roth LK, Taylor HS. Risks of smoking to reproductive health: assessment of women's knowledge. Am J Obstet Gynecol. 2001;184(5):934-9.

WHO. Global prevalence of infertility, infecundity and childlessness, 2021. WHO. Available at: https://www.who.int/reproductivehealth/topics/infertility/burden/en/. Accessed on 12 June 2023.

The Diplomat. India’s Hidden Infertility Struggles, 2020. Available at: https://thediplomat.com/2018/05/indiashiddeninfertility-struggles/. Accessed on 12 June 2023.

Katole A, Saoji AV. Prevalence of Primary Infertility and its Associated Risk Factors in Urban Population of Central India: A Community-Based Cross-Sectional Study. Indian J Community Med. 2019;44(4):337-41.

Campaign for Tobacco-Free Kids. World’s Largest Tobacco Use Study Shows Vast Scope of Tobacco Epidemic and Urgent Need for Countries to Act, 2012. Available at: https://www.tobaccofreekids.org/press-releases/2012_08_16_lancet. Accessed on 12 June 2023.

GATS2. Fact Sheet, India, 2016-17, 2017. Available at: https://www.tobaccofreekids.org/assets/global /GATS_India_2016-17_FactSheet. Accessed on 12 June 2023.

WHO. Tobacco in India, 2021. Available at: https://www.who.int/india/health-topics/t. Accessed on 12 June 2023.

American Cancer Centre. Is Any Type of Tobacco Product Safe?, 2021. Available at: https://www.cancer.org/cancer/cancercauses/tobacco-and-cancer/is-any-type-of-smoking-safe. Accessed on 12 June 2023.

John RM, Sung HY, Max W. Economic cost of tobacco use in India, 2004. Tob Control. 2009;18(2):138-43.

India Environmental Portal. Economic burden of tobacco related diseases in India: executive summary - India Environment Portal, 2021. Available at: http://www.indiaenvironmentportal.org.in/content/393313/economic-burden-of-tobacco-relateddiseasesin-india-executive-summary/. Accessed on 12 June 2023.

Statista. India - tax revenue from cigarettes, 2019. Available at: https://www.statista.com/statistics/697947/taxrevenue-from-cigarettes-india/. Accessed on 12 June 2023.

Practice Committee of the American Society for Reproductive Medicine. Electronic address: asrm@asrm.org; Practice Committee of the American Society for Reproductive Medicine. Smoking and infertility: a committee opinion. Fertil Steril. 2018;110(4):611-8.

Baird DD, Wilcox AJ. Cigarette smoking associated with delayed conception. JAMA. 1985;253(20):2979-83.

Bolumar F, Olsen J, Boldsen J. Smoking reduces fecundity: a European multicenter study on infertility and subfecundity. The European Study Group on Infertility and Subfecundity. Am J Epidemiol. 1996;143(6):578-87.

Howe G, Westhoff C, Vessey M, Yeates D. Effects of age, cigarette smoking, and other factors on fertility: findings in a large prospective study. Br Med J (Clin Res Ed). 1985;290(6483):1697-700.

Australia. Tobacco in Australia, 2021. Available at: https://www.tobaccoinaustralia.org.au/chapter7cessation/7-7-personal-factorsassociated. Accessed on 12 June 2023.

Park EW, Schultz JK, Tudiver F, Campbell T, Becker L. Enhancing partner support to improve smoking cessation. Cochrane Database Syst Rev. 2004;(3):CD002928.

Dollar KM, Homish GG, Kozlowski LT, Leonard KE. Spousal and alcohol-related predictors of smoking cessation: a longitudinal study in a community sample of married couples. Am J Public Health. 2009;99(2):231-3.

Foulstone AR, Kelly AB, Kifle T. Partner influences on smoking cessation: A longitudinal study of couple relationships. J Subst Use. 2017;22(5):501-6.

Stewart MJ, Brosky G, Gillis A, Jackson S, Johnston G, Kirkland S, et al. Disadvantaged women and smoking. Can J Public Health. 1996;87(4):257-60.

Siahpush M, Borland R, Scollo M. Smoking and financial stress. Tob Control. 2003;12(1):60-6.

Kutlu MG, Gould TJ. Nicotine modulation of fear memories and anxiety: Implications for learning and anxiety disorders. Biochem Pharmacol. 2015;97(4):498-511.

Azghdy SB, Simbar M, Vedadhir A. The emotional-psychological consequences of infertility among infertile women seeking treatment: Results of a qualitative study. Iran J Reprod Med. 2014;12(2):131-8.

Amos A. Women and smoking. Br Med Bull. 1996;52(1):74-89.

Goel S, Tripathy JP, Singh RJ, Lal P. Smoking trends among women in India: Analysis of nationally representative surveys (1993-2009). South Asian J Cancer. 2014;3(4):200-2.

WHO. Gender and tobacco control: a policy brief. Geneva: WHO; 2007.

Cooper GS, Baird DD, Hulka BS, Weinberg CR, Savitz DA, Hughes CL. Follicle-stimulating hormone concentrations in relation to active and passive smoking. Obstet Gynecol. 1995;85(3):407-11.

Barbieri RL, McShane PM, Ryan KJ. Constituents of cigarette smoke inhibit human granulosa cell aromatase. Fertil Steril. 1986;46(2):232-6.

MacMahon B, Trichopoulos D, Cole P, Brown J. Cigarette smoking and urinary estrogens. N Engl J Med. 1982;307(17):1062-5.

Butts SF, Sammel MD, Greer C, Rebbeck TR, Boorman DW, Freeman EW. Cigarettes, genetic background, and menopausal timing: the presence of single nucleotide polymorphisms in cytochrome P450 genes is associated with increased risk of natural menopause in European-American smokers. Menopause. 2014;21(7):694-701.

Plante BJ, Cooper GS, Baird DD, Steiner AZ. The impact of smoking on antimüllerian hormone levels in women aged 38 to 50 years. Menopause. 2010;17(3):571-6.

Zenzes MT, Krishnan S, Krishnan B, Zhang H, Casper RF. Cadmium accumulation in follicular fluid of women in in vitro fertilization-embryo transfer is higher in smokers. Fertil Steril. 1995;64(3):599-603.

Nemr A, Al-Shawaf T, Sabatini L, Wilson C, Lower AM, Grudzinskas JG. Effect of smoking on ovarian reserve and ovarian stimulation in in-vitro fertilization and embryo transfer. Hum Reprod. 1998;13(8):2192-8.

Waylen AL, Metwally M, Jones GL, Wilkinson AJ, Ledger WL. Effects of cigarette smoking upon clinical outcomes of assisted reproduction: a meta-analysis. Hum Reprod Update. 2009;15(1):31-44.

Freeman EW, Sammel MD, Lin H, Gracia CR. Anti-mullerian hormone as a predictor of time to menopause in late reproductive age women. J Clin Endocrinol Metab. 2012;97(5):1673-80.

Said TM, Ranga G, Agarwal A. Relationship between semen quality and tobacco chewing in men undergoing infertility evaluation. Fertil Steril. 2005;84(3):649-53.

Sunanda P, Panda B, Dash C, Ray PK, Padhy RN, Routray P. Prevalence of abnormal spermatozoa in tobacco chewing sub-fertile males. J Hum Reprod Sci. 2014;7(2):136-42.

Pasqualotto FF, Umezu FM, Salvador M, Borges E, Sobreiro BP, Pasqualotto EB. Effect of cigarette smoking on antioxidant levels and presence of leukocytospermia in infertile men: a prospective study. Fertil Steril. 2008;90(2):278-83.

Sofikitis N, Miyagawa I, Dimitriadis D, Zavos P, Sikka S, Hellstrom W. Effects of smoking on testicular function, semen quality and sperm fertilizing capacity. J Urol. 1995;154(3):1030-4.

Chapman S, MacKenzie R. The global research neglect of unassisted smoking cessation: causes and consequences. PLoS Med. 2010;7(2):e1000216.

National Health Portal Of India. Quit Tobacco, 2021. Available at: https://www.nhp.gov.in/quit-tobacco. Accessed on 12 June 2023.

Fredricsson B, Gilljam H. Smoking and reproduction. Short and long term effects and benefits of smoking cessation. Acta Obstet Gynecol Scand. 1992;71(8):580-92.

Hughes EG, Brennan BG. Does cigarette smoking impair natural or assisted fecundity? Fertil Steril. 1996;66(5):679-89.

Windsor R, Oncken C, Henningfield J, Hartmann K, Edwards N. Behavioral and pharmacological treatment methods for pregnant smokers: issues for clinical practice. J Am Med Womens Assoc (1972). 2000;55(5):304-10.

Cahill K, Stevens S, Perera R, Lancaster T. Pharmacological interventions for smoking cessation: an overview and network meta-analysis. Cochrane Database Syst Rev. 2013;2013(5):CD009329.

Ebbert JO, Elrashidi MY, Stead LF. Interventions for smokeless tobacco use cessation. Cochrane Database Syst Rev. 2015;2015(10):CD004306.