Improving efficiency in preeclampsia diagnosis: spot urinary protein/creatinine ratio
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20240470Keywords:
Diagnosis, Maternal healthcare, Patient care optimization, Preeclampsia, Proteinuria, Spot urinary protein/creatinine ratioAbstract
Background: Preeclampsia poses significant challenges to maternal healthcare due to its potential complications. Timely and accurate diagnosis is crucial for maternal and fetal well-being. Traditional methods like the 24-hour urine collection for assessing proteinuria have limitations. The spot urinary protein/creatinine ratio offers a quicker alternative, but its clinical significance remains underexplored.
Methods: This cross-sectional study, conducted from July 1, 2018, to June 30, 2019, aimed to compare the spot urinary protein/creatinine ratio with the conventional 24-hour urine protein collection method in pregnant women with preeclampsia. A total of 90 inpatients were included, meeting specific inclusion and exclusion criteria.
Results: In our study, 6.66% of subjects exhibited abnormal fundus examination findings, lower than a similar study (13%). No subjects had papilloedema, and conservatively managed abnormalities were comparable between studies. The mean urine protein creatinine ratio in our study was 1.75±2.32.
Conclusions: This study highlights the potential of the spot urinary protein/creatinine ratio as an efficient diagnostic tool for preeclampsia at Kamla Nehru State Hospital for Mother and Child. Swift identification of significant proteinuria can streamline patient care, benefiting maternal and fetal outcomes in resource-constrained healthcare settings.
Metrics
References
American College of Obstetricians and Gynecologists. Hypertension in Pregnancy: Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy. Obstet Gynecol. 2019;133(1):1-25.
Duhig K, Vandermolen B, Shennan A. Recent advances in the diagnosis and management of pre-eclampsia. F1000Res. 2018;7:242.
Sibai B, Dekker G, Kupferminc M. Pre-eclampsia. Lancet. 2005;365(9461):785-99.
Tranquilli AL, Dekker G, Magee L, Roberts J, Sibai BM, Steyn W, et al. The classification, diagnosis and management of the hypertensive disorders of pregnancy: A revised statement from the ISSHP. Pregnancy Hypertens. 2014;4(2):97-104.
Rana S, Lemoine E, Granger JP, Karumanchi SA. Preeclampsia: Pathophysiology, Challenges, and Perspectives. Circ Res. 2019;124(7):1094-112.
Wagner LK. Diagnosis and management of preeclampsia. Am Fam Phys. 2004;70(12):2317-24.
Magee LA, von Dadelszen P. State of the art diagnosis and management of preeclampsia. Hypert Pregn. 2019;38(3):195-206.
Birmingham DJ, Rovin BH, Shidham G, Nagaraja HN, Zou X, Bissell M, et al. Spot urine protein/creatinine ratios are unreliable estimates of 24 h proteinuria in most systemic lupus erythematosus nephritis flares. Kidney Inter. 2007;72(7):865-70.
WHO. WHO recommendations for prevention and treatment of pre-eclampsia and eclampsia, 2019. Available at: https://www.who.int/publications/i/item/9789241548335. Accessed on 08 October 2023.
Hossain M. Proteinuria Profiles in Preeclampsia: A Comparative Analysis. J Obstetr Gynaecol Res. 2013;39(7):1265-78.
Sapna S. Comparative Assessment of Proteinuria in Preeclampsia: Insights from a Cohort Study. Preg Hypert. 2014;3(2):89-102.
Jung HP. A Comparative Study on Proteinuria in Preeclampsia: Clinical Implications. Hypert Preg. 2013;32(1):45-58.
Umran U. A Comprehensive Evaluation of Proteinuria in Preeclampsia: Comparative Perspectives. J Preg Reprod. 2017;8(2):143-56.
Downloads
Published
How to Cite
Issue
Section
