Association of maternal serum zinc status with neonatal birth weight

Authors

  • Shahina Begum Department of Obstetrics and Gynecology, Colonel Maleque Medical College Hospital, Manikganj, Bangladesh
  • Sharmeen Mahmood Department of Obstetrics and Gynecology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20240119

Keywords:

Association, Maternal serum zinc status, Neonatal birth weight

Abstract

Background: Zinc, a vital micronutrient, plays a significant role in cellular growth and immune function. Insufficient maternal zinc levels can impact fetal growth, leading to low birth weight, a risk factor for neonatal morbidity and mortality. The aim of this study was to evaluate the association of maternal serum zinc status with neonatal birth weight.

Methods: This case-control study was conducted in Department of Obstetrics and Gynaecology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladeshfrom November 2019 to October 2021. A total of 60 women in their postnatal period were included in this study among which 30 women having a baby weighing < 2.5 kg were considered as the cases and 30 women having babies weighing ≥ 2.5 kg were enrolled as the controls.

Results: In the present study, none of the socio-demographic characteristics in both case and control groups were statistically significant (p > 0.05). Mean BMI was 23.88±1.36 kg/m2 in cases and 24.39±1.39 kg/m2 in controls, with 16.7% of cases overweight (p>0.05). Cases had lower maternal serum zinc (58.33±27.63 mcg/dL) than controls (82.96±16.94 mcg/dL), significantly affecting neonatal birth weight (p=0.001, r=+0.406). Low zinc levels (<68 mcg/dL) increased the risk of birth weight <2.500 Kg by nearly six times (OR 5.67, 95% CI 1.84-17.49; p=0.002).

Conclusions: From the findings, it can be concluded that serum zinc status is associated with the birth weight of the neonates. Low serum level of zinc is related to neonatal LBW.

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Published

2024-01-29

How to Cite

Begum, S., & Mahmood, S. (2024). Association of maternal serum zinc status with neonatal birth weight. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 13(2), 259–264. https://doi.org/10.18203/2320-1770.ijrcog20240119

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Original Research Articles