Association of postmenopausal bleeding with endometrial cancer
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20234070Keywords:
PMB, Endometrial cancer, Transvaginal sonography, TVUSAbstract
Background: Uterine cancer, also clinically referred to as endometrial cancer, stands out as the most prevalent cancer within the reproductive system of women. Notably, approximately 80% of women experiencing postmenopausal bleeding (PMB) with an endometrial thickness of ≥4 mm exhibit localized pathological lesions in the uterine cavity. This study aimed to assess the association of PMB with endometrial cancer.
Methods: This prospective study was conducted at the department of obstetrics and gynecology, delta medical college and hospital, Dhaka, Bangladesh from July 2018 to June 2019. The study comprised 1000 patients selected through purposive sampling, adhering to specific inclusion and exclusion criteria. Microsoft office tools were employed for data processing and analysis. The analytical approach employed was descriptive in nature.
Results: The study revealed that the highest percentage of patients (20.20%) exhibited abnormal endometrial hyperplasia, followed by carcinoma cervix (19.2%) and endometrial cancer (16.7%). Additionally, a significant portion of the participants, constituting 40.30%, had co-existing hypertension, while 38.1% had diabetes mellitus, and 34.0% had dyslipidemia. Notably, 65.9% of patients diagnosed with endometrial carcinoma displayed an endometrial thickness exceeding 4 mm.
Conclusions: PMB is not statistically significant for endometrial cancer, but prompt evaluation is essential to exclude malignancy. Transvaginal ultrasonography (TVUS) is a reasonable first-line approach, and invasive sampling is recommended when the endometrial thickness exceeds 4 mm.
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