Correlation between vitamin D levels in third trimester and postpartum hemorrhage

Authors

  • Poornima H. N. Department of Obstetrics and Gynecology, Hassan Institute of Medical Sciences, Hassan, Karnataka, India
  • Nayanashree V. Department of Obstetrics and Gynecology, Hassan Institute of Medical Sciences, Hassan, Karnataka, India
  • Premalatha H. L. Department of Obstetrics and Gynecology, Hassan Institute of Medical Sciences, Hassan, Karnataka, India
  • Nirmala Doreswamy Department of Obstetrics and Gynecology, Hassan Institute of Medical Sciences, Hassan, Karnataka, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20240133

Keywords:

Postpartum hemorrhage, Uterine atony, Vitamin D

Abstract

Background: The aim of this study was to assess the correlation between antenatal vitamin D levels and postpartum hemorrhage.

Methods: An analytical study was conducted among 385 term pregnant women admitted at Hassan institute of Medical Sciences and who went in spontaneous onset of labour or induced labour. Basic demographic details were noted. Vitamin D levels were assessed on admission in these patients prior to childbirth. Incidence of postpartum haemorrhage among these patients after delivery were noted and analysed.

Results: Vitamin D levels were deficient in 225 (58.5%) antenatal women in the study. The overall rates of atonic postpartum haemorrhage were higher in vitamin D deficient women that is 19 (54.2%) when compared to woman having normal vitamin D levels.

Conclusions: Our results suggest that vitamin D deficiency is highly prevalent among pregnant woman and is a risk factor for atonic postpartum hemorrhage. Hence antenatal supplementation of vitamin D could help prevent vitamin D deficiency and uterine atony.

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References

Friedman AJ. Obstetric Hemorrhage. J Cardiothorac Vasc Anesth. 2013;27(4 Suppl):S44-8.

Heaston DK, Mineau DE, Brown BJ, Miller FJ Jr. Transcatheter arterial embolization for control of persistent massive puerperal hemorrhage after bilateral surgical hypogastric artery ligation. AJR Am J Roentgenol. 1979;133(1):152-4.

Callaghan WM, Kuklina EV, Berg CJ. Trends in postpartum hemorrhage: United States, 1994-2006. Am J Obstet Gynecol. 2010;202(4):353e1-6.

Holick MF. Vitamin D deficiency. NB Engl J Med. 2007;357(3):266-81.

Van der Pligt, Willcox J, Szymlek-Gay E, Murray E, Worsley A, Daly R. Associations of maternal vitamin D deficiency with pregnant and neonatal complications in developing countries: a systematic review. Nutrients. 2018;10(5):640.

Kaushal M, Magon N. Vitamin D in pregnancy: A metabolic outlook. Ind J Endocrinol Metab. 2013;17(1):76-82.

Aghajafari F, Nagulesapillai T, Ronksley PE, Tough SC, O’Beirne M, Rabi DM. Association between maternal serum 25-hydroxyvitamin D level and pregnancy and neonatal outcomes: systematic review and meta-analysis of observational studies. BMJ. 2013;346(26 4):f1169.

Dawodu A, Saadi HF, Bekdache G, Javed Y, Altaye M, Hollis BW. Randomized controlled trial (RCT) of vitamin D supplementation in pregnancy in a population with endemic vitamin D deficiency. J Clin Endocrinol Metab. 2013;98(6):2337-46.

Rostami M, Tehrani FR, Simbar M, Bidhendi Yarandi R, Minooee S, Hollis BW, et al. Effectiveness of prenatal vitamin D deficiency screening and treatment program: a stratified randomized field trial. J Clin Endocrinol Metab. 2018;103(8):2936-48.

Fu CW, Liu JT, Tu WJ, Yang JQ, Cao Y. Association between serum 25-hydroxyvitamin D levels measured 24 hours after delivery and postpartum depression. BJOG. 2015;122(12):1688-9.

Riaz A,Ahmed A, Sultana N, Majeed T, Mahmood Z. Vitamin D and uterine muscle contraction in pregnant women after delivery. PJHMS. 2020;29(2.25):29-60.

Khan SM, Saeed M, Mustafa G, Durrani HD. Uterine atony; association of low serum vitamin D. Professional Med J. 2014;21(6):1117-21.

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Published

2024-01-29

How to Cite

H. N., P., V., N., H. L., P., & Doreswamy, N. (2024). Correlation between vitamin D levels in third trimester and postpartum hemorrhage. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 13(2), 355–357. https://doi.org/10.18203/2320-1770.ijrcog20240133

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Original Research Articles