Feto-maternal outcome in term and late term pregnancies following induction of labour with misoprostol
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20241426Keywords:
Feto-maternal outcome, Induction of labour, Period of gestationAbstract
Background: Induction of labour is the artificial initiation of labour before its spontaneous onset for the purpose of achieving vaginal delivery of the feto-placental unit. It is a common obstetric procedure which is indicated when the benefits to mother or fetus outweigh the benefits of continuing the pregnancy. Most common indication for induction is postdated pregnancy.
Methods: Longitudinal Study carried out in department of obstetrics and gynaecology, RIMS, Imphal, Manipur, conducted for duration of two calendar years, with effect from January 2021 in 168 primigravidas who had reached full term or late term pregnancy admitted in ante-natal ward of RIMS, Obstetrics and Gynaecology department.
Results: Study was conducted on 168 pregnant women, most of the participants belonged to the age group of 18-34 years (77.9%). Vaginal delivery was the most common mode of delivery (64.8%). Most of the babies (72%) delivered were having birth weight of between 2.5 kg to 3.9 kg. PPH and uterine hyperstimulation are comparatively more in the late term pregnancy as compared to full term pregnancy. Meconium-stained liquor was slightly more in late term pregnancy group as compared to full term pregnancy. Babies delivered by full term pregnant women were having better APGAR score in 1 minute and 5 minutes than the babies delivered by late term pregnancy.
Conclusions: Late term Pregnancy is comparatively common in low socio-economic group. The CS rate is comparatively high in Late term pregnancy as compared to Full Term Pregnancy. Poor APGAR score is highly associated with Late term Pregnancy outcome.
Metrics
References
Osaheni LL, Azubuike KO, Anthony I, Chikezie NO, Leonard OA. Obstetric outcome and significance of labour induction in a health resource poor setting. Obstet Gynecol Int. 2014;10(1):115-21.
Zarko A, Nasreen A, Andrew W, Cochrane. Oral misoprostol for induction of labour. Obstet Gynecol. 2014;6(2):210-4.
Gabriele S, Luigi DC, Giuseppe MM, Johanna QN, Antonio R. Induction of labour at full-term pregnant women with uncomplicated singleton pregnancy. AJOGS. 2019;7(4):222-9.
Ulla-Britt W, Sissel S, Anna W, Marten A, Christina B, Sophia BW, et al. Induction of labour at 41 weeks versus expectant management and induction of labour at 42 weeks. BMJ. 2019;367:161.
Dutta DC, textbook of Obstetrics including perinatology and contraception. 8th ed. New Delhi: Jaypee Brothers Medical Publishers; 2015.
Sanchez-Ramos L, Kaunitz AM, Wears RL, Delke I. Labor induction with 25 mcg versus 50 mcg intravaginal misoprostol :a systematic review. Obstet Gynecol. 2002;99:145-55.
Farhat N, Amina J, Sara S, Altaf B, Amtullah Z. Neonatal Outcome in Post-term Pregnancy. PJMHS. 2010;4(3):12-9.
Lawani OL, Onyebuchi AK, Iyoke CA, Okafo CN, Ajah LO. Obstetric outcome and significance of labour induction in a health resource poor setting. Obstet Gynecol Int. 2014;134(17):1765-73.
Kim HI, Choo SP, Han SW, Kim EH. Benefits and risks of induction of labor at 39 or more weeks in uncomplicated nulliparous women: a retrospective, observational study. Obstet Gynecol Sci. 2019;62(1): 19-26.
Sabina L, Subedu S, Basudev B, Rupak B. Outcome of Induction of labour:a prospective study. An Int Den Med Res. 2016;2(6):2395-414.
Punya BS, Sailakshmi MPA. Study of Post dated and term Pregnancy with fetomaternal outcome at RRMCH. Indian J Obstet Gynaecol Res. 2017;4(2): 179-83.
Verma V, Kanti V, Shree P. Maternal and fetal outcome in post term pregnancy. Int J Reprod Contracep Obstet Gynecol. 2017;6:2897-9.
Chen W, Xue J, Peprah MK, Wen SW, Walker M, Gao Y, et al. A systematic review and network meta-analysis comparing the use of Foley catheters, misoprostol, and dinoprostone for cervical ripening in the induction of labour. BJOG. 2016;123(3):346-54.
Rydahl, Eva, Lena, Juhl, Mette. Effects of induction of labor prior to post term in low risks pregnancies:a systematic review. JBISRIR. 2017;17:209-47.
Kreft M, Krahenmann F, Roos M. Maternal and neonatal outcome of labour induction at term comparing two regimens of misoprostol. J Perinat Med. 2014;42(10):2013-215.
Gurung SD, Shrestha J, Gauchan E, Subedi A, Shrestha A. A Study of the feto-maternal outcomes at late-term pregnancy in a tertiary level hospital in western Nepal. Nepal J Med Sci. 2022;7(1):62-7.