Obstetric perinatal outcomes in COVID-19-positive pregnant women
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20240161Keywords:
Demographic, Clinical, Covid-19, Pregnant, Obstetrics, PainAbstract
Background: In December 2019, a novel coronavirus disease (COVID-19) emerged in Wuhan, China, with an incredible infection rate. The vertical transmission of COVID-19 is uncertain. Pregnant females are considered a high‑risk group for the prevention and control of various communicable diseases. This study aimed to assess the obstetric perinatal outcomes in Covid-19 positive pregnant women.
Methods: This was a descriptive cross-sectional study and was conducted in the department of Obstetrics and Gynaecology, Mugda Medical College, Dhaka, Bangladesh from 26 March 2021 to 21 July 2022. A total of 94 pregnant women diagnosed as COVID-19 patients by RT-PCR tests were enrolled in this study as the study subjects purposively. Data were analysed by using MS Office tools.
Results: In the study, 23% of participants experienced lower abdominal pain as a pregnancy symptom, with 11%, 4%, and 9% reporting premature rupture of membranes, decreased fetal movement, and antepartum haemorrhage, respectively. Among the participants, 45% had vaginal deliveries, 15% had assisted vaginal deliveries, and 40% underwent lower uterine caesarean sections. Notably, 11% required ICU admission. The study recorded maternal and neonatal mortality rates of 2% and 4%, respectively, and 9% of babies needed incubation. The average APGAR score (5 minutes) was 6.8±0.2, and the mean birth weight was 2.5±0.3.
Conclusions: Lower abdominal pain and premature rupture of membranes (PROM) may be considered some major pregnancy symptoms for COVID-19-positive pregnant women. For such cases, proper facilities for LUCS, ICU and incubation are needed.
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References
McBride O, Murphy J, Shevlin M. Monitoring the psychological, social, and economic impact of the COVID‐19 pandemic in the population: context, design and conduct of the longitudinal COVID‐19 psychological research consortium (C19PRC) study. Int J Methods Psychiatr Res. 2021;30(1):e1861.
Singh S, Nair VG, Singh VV. Pregnancy‐specific concerns and psychological impact of COVID‐19 on antenatal women. Gynecol Obstet Reprod Med. 2021:1‐6.
Schwartz DA. An analysis of 38 pregnant women with COVID-19, their newborn infants, and maternal-fetal transmission of SARS-CoV-2: Maternal coronavirus infections and pregnancy outcomes. Arch Pathol Lab Med. 2020;144(7):799-805
Arbabzadeh T, Noori N, Najafian A, Ghasemi M. Assessment of corona in pregnant women: Epidemiology, clinical signs, prevention and treatment. J Complement Med Res. 2020;11(3):118-30.
Badr DA, Mattern J, Carlin A, Cordier AG, Maillart E, El Hachem L, et al. Are clinical outcomes worse for pregnant women at≥ 20 weeks’ gestation infected with coronavirus disease 2019? A multicenter case-control study with propensity score matching. Am J Obstet Gynecol. 2020;223(5):764-8.
Yu N, Li W, Kang Q, Xiong Z, Wang S, Lin X, et al. Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: A retrospective, single-center, descriptive study. Lancet Infect Dis. 2020;20(5):559-64.
Anand P, Yadav A, Debata P, Bachani S, Gupta N, Gera R. Clinical profile, viral load, management and outcome of neonates born to COVID-19 positive mothers: A tertiary care center experience from India. Eur J Pediatr. 2020;180(2):547-59.
Centers for Disease Control and Prevention. Centers for Disease Control and Prevention Coronavirus Disease 2019 (COVID-19) 2020. United States: Centers for Disease Control and Prevention; 2020.
Shook LL, Atyeo CG, Yonker LM, Fasano A, Gray KJ, Alter G, Edlow AG. Durability of anti-spike antibodies in infants after maternal COVID-19 vaccination or natural infection. JAMA. 2022a;327(11):1087-9.
Holland, Cindra, Crystal Hammond, and Misty M. Richmond. "COVID-19 and pregnancy: risks and outcomes." Nursing for Women's Health 27.1. 2023:31-41.
World Medical Association. World Medical Association Declaration of Helsinki. Ethical principles for medical research involving human subjects. Bulletin of the World Health Organization. 2001;79(4):373-4.
Voigt, Paul, and Axel von dem Bussche. Enforcement and fines under the GDPR. The EU General Data Protection Regulation (GDPR). Springer, Cham, 2017;201-217.
Espiritu, Adrian I. Clinical Outcomes of COVID-19 Infection in Pregnant and Nonpregnant Women: Results from The Philippine CORONA Study. Vaccines. 2023;11(2):226.
Leal LF, Merckx J, Fell DB, Kuchenbecker R, Miranda AE, de Oliveira WK, et al. Characteristics and Outcomes of Pregnant Women with SARS-CoV-2 Infection and Other Severe Acute Respiratory Infections (SARI) in Brazil from January to November 2020. Braz J Infect Dis. 2021;25:101620.
Yan J, Guo J, Fan C, Juan J, Yu X, Li J, et al. Coronavirus disease 2019 in pregnant women: a report based on 116 cases Am J Obstet Gynecol, 2020;223(1):111.e1-111.e14.
Pierce-Williams RAM, Burd J, Felder L. The clinical course of severe and critical coronavirus disease 2019 in hospitalized pregnancies: a United States cohort study. Am J Obstet Gynecol MFM. 2020;2:100134.
Ackerman, Christina M. Clinical and pregnancy outcomes of coronavirus disease 2019 among hospitalized pregnant women in the United States." Open Forum Infectious Diseases. US: Oxford University Press; 2022;9(2).
Woodworth KR, Olsen EO, Neelam V. CDC COVID-19 Response Pregnancy and Infant Linked Outcomes Team; COVID-19 Pregnancy and Infant Linked Outcomes Team (PILOT). Birth and infant outcomes following laboratory-confirmed SARS-CoV-2 infection in pregnancy - SET-NET, 16 jurisdictions, March 29-October 14, 2020. MMWR Morb Mortal Wkly Rep. 2020;69:1635-40.
Jering KS, Claggett BL, Cunningham JW. Clinical characteristics and outcomes of hospitalized women giving birth with and without COVID-19. JAMA Intern Med. 2021;181:714-7.
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