Scrub typhus masquerading as puerperal sepsis

Authors

  • Anju Singh Department of Obstetrics and Gynecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  • Gaurav Khastgir Department of Obstetrics and Gynecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India https://orcid.org/0009-0004-6462-6501
  • Pradip Kumar Saha Department of Obstetrics and Gynecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  • Rashmi Bagga Department of Obstetrics and Gynecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  • Vikas Suri Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20240494

Keywords:

Scrub typhus, Puerperal fever, Puerperal sepsis, Acute undifferentiated febrile illness

Abstract

Scrub typhus is a zoonotically transmitted febrile illness caused by Orientia tsutsugamushi and transmitted by the larval stage of the leptotrombiculid mite. It is the most common rickettsial illness worldwide and has re-emerged as a major cause of Acute Undiffrentiated Febrile Illness (AUFI). It has a varied presentation ranging from a mild self-limiting illness to a life threatening condition with multi organ failure in 35 to 50% cases. Acute onset fever with pain abdomen, rashes, lymphadenopathy and eschars are the usual manifestations. The presentation, however, may be varied in pregnancy and the postpartum period due to altered immunological response of the body. A 33 year old lady presented on day 13 post-partum with high grade fever and hypotensive shock. An initial diagnosis of puerperal sepsis was made and empirical antibiotics started. Due to persistent high grade fever, with fluid refractory hypotension, a complete septic work up including Scrub typhus serology was sent which was found to be positive. Injection doxycycline was added to the treatment regimen following which the fever and rashes subsided and general condition improved.

Metrics

Metrics Loading ...

References

Coleman RE, Monkanna T, Linthicum KJ, Strickman DA, Frances SP, Tanskul P, et al. Occurrence of Orientia tsutsugamushi in small mammals from Thailand. Am J Trop Med Hyg. 2003;69(5):519-24.

Mcphee SJ, Papadakis MA, Lm T. Current Medical Diagnosis and Treatment. Current Medical Diagnosis and Treatment. McGraw Hill: 2008.

Jiang J, Richards AL. Scrub Typhus: No Longer Restricted to the Tsutsugamushi Triangle. Trop Med Infect Dis. 2018;3(1):11.

Taylor AJ, Paris DH, Newton PN. A Systematic Review of Mortality from Untreated Scrub Typhus (Orientia tsutsugamushi). PLoS Negl Trop Dis. 2015;9(8):e0003971.

Isaac R, Varghese GM, Mathai EJM, Joseph I. Scrub typhus: prevalence and diagnostic issues in rural Southern India. Clin Infect Dis. 2004;39(9):1395-6.

Varghese GM, Trowbridge P, Janardhanan J, Thomas K, Peter JV, Mathews P, et al. Clinical profile and improving mortality trend of scrub typhus in South India. Int J Infect Dis. 2014;23:39-43.

Watt G, Parola P. Scrub typhus and tropical rickettsioses. Curr Opin Infect Dis. 2003;16(5):429-36.

Kawamura A, Tanaka H. Rickettsiosis in Japan. Jpn J Exp Med. 1988;58(4):169-84.

Mathai E, Rolain JM, Verghese GM, Abraham OC, Mathai D, Mathai M, et al. Outbreak of scrub typhus in southern India during the cooler months. Ann N Y Acad Sci. 2003;990:359-64.

Vivekanandan M, Mani A, Priya YS, Singh AP, Jayakumar S, Purty S. Outbreak of scrub typhus in Pondicherry. J Assoc Physicians India. 2010;58:24-8.

Girija S, Rajan A, Sathiyanarayanan J, Mangaiyarkarasi T, Saban P, Sunil S, et al. Scrub typhus-An emerging disease in South India. IJRRMS. 2013;3(4):11-3.

Kim DM, Kim SW, Choi SH, Yun NR. Clinical and laboratory findings associated with severe scrub typhus. BMC Infect Dis. 2010;10:108.

Varghese GM, Janardhanan J, Trowbridge P, Peter JV, Prakash JA, Sathyendra S, et al. Scrub typhus in South India: clinical and laboratory manifestations, genetic variability, and outcome. Int J Infect Dis. 2013;17(11):e981-7.

Mahajan SK, Rolain JM, Kashyap R, Gupta D, Thakur S, Sharma A, Kaushal SS, Raoult D. Scrub typhus complicating pregnancy. J Assoc Physicians India. 2009;57:720-1.

Downloads

Published

2024-02-27

Issue

Section

Case Reports