Utility in the obstetric high dependency unit and intensive care unit in tertiary medical center in Ethiopia: a comparative cross-sectional study
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20240769Keywords:
Maternity, HDU, Outcome, Utility, ICUAbstract
Background: Globally, an estimated 10.7 million women have died due to obstetric complications in the last two decades, and two-thirds of these deaths occurred in sub-Saharan Africa. This study aims to assess the utility of the obstetric high dependency unit and intensive care unit and maternal outcome in a tertiary medical center in Ethiopia.
Methods: A comparative cross-sectional study was conducted on critically ill obstetric clients admitted to St. Paul's Hospital Millennium medical college obstetric HDU from October 2020 to September 2022 and before the establishment of the obstetric HDU (who were admitted to the medical ICU). Binary and multivariate logistic regression was conducted to identify factors associated with maternal mortality before the establishment of the maternal HDU.
Results: The minimum duration in both units was one day. The maximum duration was 14 days for HDU and 26 days for ICU. Following the establishment of the maternity HDU, the ICU admission rate decreased to 1.2 per 1000 deliveries. Obstetric patients diagnosed with DIC and HELLP syndrome upon admission to the ICU had a 4.9 times higher risk of mortality compared to their counterparts. Obstetric women admitted to the ICU and treated with inotropic agents or vasopressors had a 33.8 times higher risk of mortality compared to their counterparts.
Conclusions: Obstetric admissions to the ICU significantly decreased following the establishment of the maternity HDU. Obstetric patients diagnosed with DIC and HELLP syndrome are more likely to develop unfavorably outcome.
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References
Ayele G, Catherine C, Abdulbasit M, Deborah L. Barriers to access and utilization of emergency obstetric care at health facilities in sub-Saharan Africa-a systematic review protocol. BMC. 2018;7(1):1-14.
Surekha T, Neha G, Poonam S, Dinesh B, Apurva R, Himanshu B, et al. Role of Obstetric High Dependency and Intensive Care Unit in Improving Pregnancy Outcome and Reducing Maternal Mortality-A Study in Rural Central India. Int J Crit Care Emerg Med. 2018; 4(2):1-9.
Guidelines for Obstetric HDU and ICU, 2016. Available at: https://nhm.gov.in/images/pdf/ programmes/maternal-health/guidelines/Guidelines_ for_Obstetric_HDU_and_ICU.pdf. Accessed on 20 June 2023.
Adeniran A, Bolaji B, Fawole A, Oyedepo O, Gbadeyan O, Ejilude O. The High Dependency Unit in the Management of Critically Ill Obstetric Patients in Low Resource Countries. Sierra Leone J Biomed Res. 2015;7(2):57-63.
Trends in maternal mortality 2000 to 2020: estimates by WHO, UNICEF, UNFPA, World Bank Group and UNDESA/Population Division, 2023. Available at: https://www.who.int/publications-detail-redirect/ 9789240068759. Accessed on 16 November 2023.
Langenegger E. Establishing an obstetric critical care unit in a South African Tertiary Hospital. Stellenbosch Univ J. 2016.
Joshi P, Kathaley M, Dashrathi R, Prasade S. Study of maternal and perinatal outcome in patients in high dependency unit (HDU) in a Tertiary Care Centre. MVP J Med Sci. 2019;6(1):78-83.
Mandal D, Shankar U, Bhattacharya P, Mandal S, Dattaray C. Obstetric patients requiring high-dependency unit admission in a tertiary referral centre. Int J Crit Illn Inj Sci. 2013;3(1):31.
Saravanakumar K, Davies L, Lewis M, Cooper G. High dependency care in an obstetric setting in the UK. Anaesthesia. 2008;63(10):1081-6.
Vanitha M, Rashmi K, Srividya S. Pregnancy related admissions to high dependency unit-clinical characteristics and outcome. Int J Clin Obstet Gynaecol. 2020;4(2):424-7.
Gu N, Zheng Y, Dai Y. Severe maternal morbidity: admission shift from intensive care unit to obstetric high-dependency unit. BMC Preg Childbirth. 2022;22(1):1-7.
Endacott R, Wilkinson R, Harrison L, Ellis H. Nursing implications of the department of health guidelines on admission to and discharge from intensive care and high dependency units. Intens Crit Care Nurs. 1996;12(2):122.
Ridley SA. Intermediate Care Facility. Clin Med. 2020;3:654-64.
Zhao Z, Han S, Yao G, Li S, Li W, Zhao Y, et al. Pregnancy-related ICU admissions from 2008 to 2016 in China: A first multicenter report. Crit Care Med. 2018;46(10):E1002-9.
in L, Chen YH, Sun W, Gong JJ, Li P, Chen JJ, et al. Risk factors of obstetric admissions to the intensive care unit. PMC. 2019;98(11):1-5.
Miglani U, Pathak AP, Laul P, Sarangi S, Gandhi S, Miglani S, et al. A study of clinical profile and fetomaternal outcome of obstetric patients admitted to intensive care unit: A prospective hospital-based study. Indian J Crit Care Med. 2020;24(11):1071-6.
Baby Sailaja K, and Renuka M. Critically ill obstetric admissions to an intensive care unit: A prospective analysis from a Tertiary Care University Hospital in South India. Indian J Crit Care Med. 2019;23(2):78-82.
Ghike S, and Asegaonkar P. Why obstetric patients are admitted to intensive care unit? A retrospective study. J Safog. 2012;4(2):90-2.
Yuqi L, Tan G, Chengming S, and Xuri S. The ICU Is Becoming a Main Battlefield for Severe Maternal Rescue in China: An 8-Year Single-Center Clinical Experience. Crit Care Med. 2017;45(11):E1106-10.
Saintrain S, De Oliveira J, De Lima SM, Bruno Z, Borges J, De Francesco D, et al. Factors associated with maternal death in an intensive care unit. Rev Bras Ter Intensiva. 2016;28(4):397-404.