Comparison between colposcopic and biopsy findings to determine the frequency cervical intraepithelial neoplasia I to III in visual inspection with acetic acid
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20240775Keywords:
Colposcopic, Biopsy, Cervical cancer, VIA, CytologicAbstract
Background: While visual inspection with acetic acid (VIA) is an effective and affordable screening tool, the determination of the severity of cervical intraepithelial neoplasia (CIN) relies heavily on the expertise of healthcare professionals and the interpretation of colposcopic and biopsy findings. The aim of this study is to compare the frequency CIN I-III in VIA positive cases with the help of colposcopic and biopsy findings.
Methods: The prospective cross sectional descriptive study conducted among the VIA positive cases (n=100) who were attending at in colposcopic clinic of department of obstetrics and gynecology, Dhaka Bangabandhu Sheikh Mujib medical university (BSMMU) during 1st June 2010 to 30th August 2010. History includes present and past illness, personal, family history, drug history and blood pressure were done.
Results: The mean duration of married life was 16.8±10.6 years and more than a half (52.0%) of the patients’ age was 15-20 years of their first intercourse. More than one fourth (27.0%) of the patients had irregular menstrual cycle and 10.0% patients were menopause. Most (72.0%) of the study patients were multipara and the mean age of 'last confinement was 7.8±6.8 years. Majority 38(38.0%) of the patient was normal, 25 (25.0%) of the study patients had CIN I and CIN II in 13 (13.0%), CIN III in 5 (5.0%), 4 (4.0%) had invasive carcinoma and 15 (15.0%) unsatisfactory colposcopy. The colposcopic related biopsy findings was observed, 27.1% of the study patients had CIN I, 12.9% had CIN II, 12.9% invasive carcinoma, 5.9% had CIN III and 5.9% had inflammatory change.
Conclusions: CIN III in colposcopic-related biopsy findings was associated with a mixture of CIN I and CIN III in colposcopic examinations. Invasive carcinoma in biopsy results was linked to a combination of CIN III and invasive carcinoma in colposcopic findings.
References
Akhter N. Visual Inspection of Cervix by Acetic Acid (VIA) and pap's smear for screening of cervical cancer-A comparative study. BSMMU, FCPS dissertation. 2005.
Ashford L, Collymore Y. Preventing Cervical Cancer Worldwide. 2005. Available at: www.prb.org. http://www.prb.org/pdf05/preventcervcancer-briefeng.pdf. Accessed on 11 January, 2024.
BEGUM NK. Evaluation of visual inspection with acetic acid (VIA) as a screening tool for cervical in developing countries. SSMC and MH, FCPS dissertation. 2008.
Bingham A, Bishop A, Coffey P, Winkler J, Bradley J, Dzuba I, et al. Factors affecting utilization of cervical cancer prevention services in low-resource settings. Salud Publica Mex. 2003;45(3):S408-16.
Cagle AJ, Hu SY, Sellors JW, Bao YP, Lim JM, Li SM, et al. Use of an expanded gold standard to estimate the accuracy of colposcopy and visual inspection with acetic acid. Int J Cancer. 2010;126(1):156-61.
Catterina F, Julia G. Critical Review. In: Visual inspection of the uterine cervix with acetic acid (VIA): A critical review and selected articles. Washington DC, Pan American Health Organization (PAHO). 2003;8.
Cremer M, Conlisk E, Maza M, Kimberley B, Ethel P, Matthew S, et al. Adequacy of visual inspection with acetic acid in women of advancing age. Int J Gynecol Obstetr. 2011;113(1):1-4.
Ferlay J, Bray F, Pisani P, Parkin DM, Globocan, 2000. 'Cancer incidnece, mortality and prevalence Worlwide, version 1.0', IARC Cancer Base, no. 5, Lyon, IARC press. 2001.
Hossain. N-Role of Colposcopy Directed Biopsy in Diagnosis of CIN-BCPS Dissertation. 2000.
Johsnson C Coventional cytology. In: Apgar BS, Brotzman GL, Spitzer M (eds). Colposcopy principles and practice. An integrated Text book and atlas. Philadelphia, WB. Sounders Company. 2002;52-6.
Carr KC, Sellors JW. Cervical Cancer Screening in Low Resource Settings Using Visual Inspection with Acetic Acid. J Midwifery Women’s Health. 2004;49(4):329-37.
Ngelangel CA, Limson GM, Cordero CP, Abelardo AD, Avila JM, Festin MR. UP-DOH CCSHOSG Acetic- acid guided visual inspection vs. cytology-based screening for cervical cancer in the Philippines. Int J Gynecol Obstetr. 2003;83(2):141-50.
Parkin DM, Bray F, Ferlay J, Pisani P. Estimating the world cancer burden: Globocan 2000. Int J Cancer. 2001;94(2):153-6.
Sayeeda S. Colposcopic Finding in Clinically Unhealthy Cervix and Incidence of CIN-A Study in a Group of Patients Attending Colposcopy Clinic in BSMMU, BCPS dissertation. 2003.
Sritipsukho P, Thaweekul Y. Accuracy of Visual Inspection with Acetic Acid (VIA) for Cervical Cancer Screening: A Systematic Review. J Med Assoc Thai. 2010;93(7):S254-61.
University of the Philippines Department of Health Cervical Cancer Screening Study Group. Kap-Behavior study, Manila. 2001.
World Health Organization. Cervical Cancer Screening in Developing Countries. Report of a WHO consultation. 2001.
