Neonatal outcome of babies born with congenital anomalies after pediatric surgery


  • Snigdha Sharma Department of Obstetrics and Gynecology, Shri Guru Ram Rai Institute of Medical Sciences, Dehradun, Uttarakhand, India
  • Arti Sharma Department of Obstetrics and Gynecology, Shri Guru Ram Rai Institute of Medical Sciences, Dehradun, Uttarakhand, India
  • Madhukar Maletha Department of Pediatric Surgery, Shri Guru Ram Rai Institute of Medical Sciences, Dehradun, Uttarakhand, India



Congenital anomalies, Stillbirths , Risk factors, Prevalence, Pediatric surgery, Neonatal mortality


Background: Congenital anomalies are the major cause of adverse neonatal outcome and mortality.  Some congenital anomalies are correctable and there is immense role of pediatric surgery in treatment of these anomalies. The aim of this study was to determine the pattern of congenital anomalies and to evaluate clinical outcome of babies after surgical intervention.

Methods: This hospital-based cross-sectional study was carried out in the Obstetrics and Gynecology department during the period of 1 year. All the delivered babies in this hospital during this period were examined by obstetricians and pediatricians for the presence of various congenital anomalies. Babies with correctable anomalies were operated by the Pediatric Surgery Department and outcome of babies at the time of discharge was included. Data were entered into a case record form and then in the excel sheet and were analyzed statistically.

Results: During the study period, 1670 babies were delivered in our institution; of which, 32 babies had congenital malformations, giving the prevalence of 1.91%. The system involved predominantly was the gastrointestinal (GI) system (80%). Pregnancy with congenital malformation were associated with malpresentation, anemia and polyhydramnios. Overall, most babies operated for pediatric surgery had good outcome.

Conclusions: Pre pregnancy high-dose folic acid supplementation, regular antenatal visits, and prenatal diagnosis are recommended for prevention, early detection and management of congenital anomalies. There is great importance of Level II and NT NB Scan. Pediatric surgery is a boon in babies with correctable anomalies.


Dursun A, Zenciroglu A, Hakan N, Karadag N, Karagol BS, Aydin B, et al. Distribution of congenital anomalies in a neonatal intensive care unit in Turkey. J Matern Fetal Neonatal Med. 2014;27(10):1069-74.

Taksande A, Vilhekar K, Chaturvedi P, Jain M. Congenital malformations at birth in Central India: A rural medical college hospital based data. Ind J Hum Genet. 2010;16(3):159-63.

Pandala P, Kotha R, Singh H, Nirmala C. Pattern of congenital anomalies in neonates at tertiary care centre in Hyderabad, India: a hospital based prospective observational study. Int J Contemp Pediatr. 2019;6:63-7.

Bakalli I, Kola E, Lluka R, Celaj E, Sala D, Gjeta I, et al. Surgical congenital anomalies in Albania: incidence, prenatal diagnosis and outcome. World J Pedia Surg. 2019;2(1):e000012.

Ara A, Kumar D, Dewan D, Digra NC. Incidence of congenital anomalies in a rural population of Jammu -A prospective study. Ind J Publ Heal. 2018;62(3):188-92.

Oluwafemi RO, Abiodun MT. Incidence, spectrum and outcome of congenital anomalies seen in a neonatal intensive care unit in Southern Nigeria. Niger Postgrad Med J. 2019;26(4):239-43.

Sitkin NA, Ozgediz D, Donkor P, Farmer DL. Congenital anomalies in low- and middle-income countries: the unborn child of global surgery. World J Surg. 2015;39(1):36-40.

Verity C, Firth H, ffrench-Constant C. Congenital abnormalities of the central nervous system. J Neurol Neuros Psych. 2003;74(Suppl 1):i3-8.

Naseha A, Iqbal Y. Incidence of congenital anomalies in tertiary health care centre. J. Evolution Med. Dent. Sci. 2016;5(67):4826-33.

Bakare TI, Sowande OA, Adejuyigbe OO, Chinda JY, Usang UE. Epidemiology of external birth defects in neonates in Southwestern Nigeria. Afr J Paediatr Surg. 2009;6(1):28-30.

Wright NJ Global PaedSurg Research Collaboration Management and outcomes of gastrointestinal congenital anomalies in low, middle and high income countries: protocol for a multicentre, international, prospective cohort study. BMJ Open. 2019;9:e030452.

Kishimba RS, Mpembeni R, Mghamba JM, Goodman D, Valencia D. Birth prevalence of selected external structural birth defects at four hospitals in Dar es Salaam, Tanzania, 2011-2012. J Glob Health. 2015;5(2):020411.

Park K. Preventive medicine in Obstetrics, Pediatrics and Geriatrics. In: Park’s Textbook of Preventive and Social Medicine. 23rd ed. Banarsidas Bhanot Publishers; 2015:577.

Mashuda F, Zuechner A, Chalya PL, Kidenya BR, Manyama M. Pattern and factors associated with congenital anomalies among young infants admitted at Bugando medical centre, Mwanza, Tanzania. BMC Res Notes. 2014;7:195.

Suguna Bai NS, Mascarene M, Syamalan K, Nair PM. An etiological study of congenital malformation in the newborn. Ind Pediatr. 1982;19(12):1003-7.

Savaskar SV, Mundada SK, Pathan AS, Gajbhiye SF. Study of various antenatal factors associated with congenital anomalies born at tertiary health centre. Int J Rece Tren Sci Technol. 2014;12(1):82.

Millman GC. Fanaroff and Martin's neonatal‐perinatal medicine diseases of the fetus and infant, 8th ed, Vols I and II. Arch Dis Child Fetal Neonatal Ed. 2006;91(6):F468.

Prajapati VJ, Kacha AR, Kakkad KM, Damor PB, Nandaniya AM. Study of congenital malformation in neonates born at tertiary care hospital. Natl J Community Med. 2015;6(1):30-4.

Francine R, Pascale S, Aline H. Congenital anomalies: prevalence and risk factors. Mortality. 2014;1(2):58-63.

Wills V, Jacob A, Sreedevi NS. Congenital anomalies: The spectrum of distribution and associated maternal risk factors in a tertiary teaching hospital. Int J Reprod Contracept Obstet Gynecol. 2017;6(4):1555-60.

Wu VK, Poenaru D, Poley MJ. Burden of surgical congenital anomalies in Kenya: a population-based study. J Trop Pediatr. 2013;59(3):195-202.

Ekenze SO, Ikechukwu RN, Oparaocha DC. Surgically correctable congenital anomalies: prospective analysis of management problems and outcome in a developing country. J Trop Pediatr. 2006;52(2):126-31.

Gasparella P, Singer G, Kienesberger B, Arneitz C, Fülöp G, Castellani C, Till H, Schalamon J. The financial burden of surgery for congenital malformations-the austrian perspective. Int J Environ Res Public Health. 2021;18(21):11166.






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