A case report of methemoglobinemia in pregnancy

Authors

  • Jyotika Gupta Department of Obstetrics and Gynaecology, New Civil Hospital, Surat, Gujarat, India
  • Sejal Patel Department of Obstetrics and Gynaecology, New Civil Hospital, Surat, Gujarat, India
  • Yogesh Parmar Department of Obstetrics and Gynaecology, New Civil Hospital, Surat, Gujarat, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20241461

Keywords:

Methemoglobinemia, Methaemoglobin, Pregnancy, Methylene blue

Abstract

Methemoglobinemia is a rare form of functional anaemia which disrupts the ability to transport oxygen effectively by the haemoglobin leading to obstetrical as well as non-obstetrical complications. Our objective was to observe the antenatal, perinatal, and post-natal outcomes in women diagnosed with methemoglobinemia. A case report of two patients of methemoglobinemia admitted in a tertiary care centre of South Gujarat. The report displays a qualitative analysis of the diagnosis and management undertaken, providing a critical evaluation of their effectiveness and implications for future clinical practice. Methemoglobinemia, while uncommon, requires awareness for timely diagnosis and effective management. Congenital cases often go unnoticed until pregnancy, with methaemoglobin levels under 20% usually not necessitating treatment. Symptomatic individuals can benefit from methylene blue and hyperbaric oxygen therapies. Avoiding certain drugs and ensuring swift diagnosis, coupled with proper counselling, can lead to favourable pregnancy outcomes.

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References

Turner MD, Karlis V, Glickman RS. The recognition, physiology, and treatment of medication induced methemoglobinemia: A case report. Anesth Prog. 2007;54:115 7.

Yang JJ, Lin N, Lv R, Sun J, Zhao F, Zhang J, et al. Methemoglobinemia misdiagnosed as ruptured ectopic pregnancy. Acta Anaesthesiol Scand. 2005;49(4):586-8.

David SR, Sawal NS, Bin Hamzah MN, Rajabalaya R. The blood blues: A review on methemoglobinemia - Treatment. J Pharmacol Pharmacother. 2018;9:1-5.

Cefalu JN, Joshi TV, Spalitta MJ, Kadi CJ, Diaz JH, Eskander JP, et al. Methemoglobinemia in the Operating Room and Intensive Care Unit: Early Recognition, Pathophysiology, and Management. Adv Ther. 2020;37(5):1714-23.

Denshaw Burke M, DelGiacco E, Curran AL, Savior DC, Kumar M. Methemoglobinemia Treatment & Management. Medscape. 2016. Available at: http://www.emedicine.medscape.com/ article/204178 treatment#showall. Accessed on 09 February 2024.

Schirmer RH, Adler H, Pickhardt M, Mandelkow E. “Lest we forget you – Methylene blue.”. Neurobiol Aging. 2011;32:2325.

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Published

2024-05-29

How to Cite

Gupta, J., Patel, S., & Parmar, Y. (2024). A case report of methemoglobinemia in pregnancy. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 13(6), 1616–1618. https://doi.org/10.18203/2320-1770.ijrcog20241461

Issue

Section

Case Reports