Prediction of preeclampsia by HDP gestosis score

Authors

  • Anupma Upadhyay Department of Obstetrics and Gynecology, MLNMC Prayagraj, Uttar Pradesh, India
  • Amrita Chaurasia Department of Obstetrics and Gynecology, MLNMC Prayagraj, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20241766

Keywords:

Gestosis, HDP score, Preeclampsia, Prediction

Abstract

Background: Preeclampsia is a complex obstetrical syndrome and an important contributor to maternal and perinatal morbidity and mortality. A large number of predictive tests and scoring systems have been proposed but ni low resource settings a cheap, quick and reliable scoring system is desirable to adequately predict the risk for all women. This study aimed to study the role of HDP gestosis score in prediction of preeclampsia.

Methods: The study was done on 400 antenatal women attending Obstetrics and Gynecology outpatient department of SRN hospital, MLNMC Prayagraj. All enrolled participants were assigned a gestosis score calculated by the ANDROID AP at first visit (<18 weeks of gestation). All women were divided in three groups according to gestosis score of 1, 2 and 3 or more. The participants were then followed throughout pregnancy and development of preeclampsia was noted.

Results: Preeclampsia developed in 13.7% of women. THE sensitivity, specificity, positive predictive value, negative predictive value and predictive accuracy of HDP gestosis score were 72.2%, 94.6%, 68.4%, 95.5% and 91.6% respectively.

Conclusions: The HDP gestosis score is a simple, cheap, mobile app. Based scoring system which allows provider to quickly assess individual woman risk-for future development of preeclampsia in busy OPD setting. HDP gestosis score is an effective tool to predict at risk women and initiate pharmacological intervention or intensive maternofetal surveillance.

References

Kenny LC, Black MA, Poston L, Taylor R, Myers JE, Baker PN, et al. Early pregnancy prediction of preeclampsia in nulliparous women, combining clinical risk and biomarkers: the Screening for Pregnancy Endpoints (SCOPE) international cohort study. Hypertension. 2014;64(3):644-52.

Poon LC, Nicolaides KH. Early prediction of preeclampsia. Obstet Gynecol Inter. 2014;2014(1):297397.

Dhinwa M, Gawande K, Jha N, Anjali M, Bhadoria AS, Sinha S. Prevalence of hypertensive disorders of pregnancy in India: a systematic review and meta-analysis. J Med Evid. 2021;2(2):105-12.

Poon LC, Shennan A, Hyett JA, Kapur A, Hadar E, Divakar H, et al. The International Federation of Gynecology and Obstetrics (FIGO) initiative on preeclampsia (PE): a pragmatic guide for first trimester screening and prevention. Int Federat Gynaecol Obstetr. 2019;145(Suppl 1):1.

FOGSI-gestosis-ICOG. Hypertensive Disorders in Pregnancy (HDP), 2019. Available at: https://www.fogsi.org/wp-content/uploads/2015/11/hdp.pdf. Accessed 01 February 2022.

MCCHS. HDP-gestosis Score, version 1.2, 2021. Available at: https://apkgk.com/hdp.gestosis.score. Accessed 01 March 2022.

Gupta M, Yadav P, Yaqoob F. A prospective study to determine the predictive ability of HDP-gestosis score for the development of pre-eclampsia. J Obstetr Gynecol India. 2022;72(6):485-91.

Mishra SS, Mohanty S, Ghadei R, Pradhan S, Majhi PP. HDP-gestosis score as a predictor of Pre-eclampsia. IJSR. 2020;9(8):25-8.

Papaioannou TG, Protogerou AD, Vrachatis D, Konstantonis G, Aissopou E, Argyris A, et al. Mean arterial pressure values calculated using seven different methods and their associations with target organ deterioration in a single-center study of 1878 individuals. Hypertens Res. 2016;39(9):640-7.

Chau K, Hennessy A, Makris A. Placental growth factor and pre-eclampsia. J Hum Hypertens. 2017;31(12):782-6.

Magee LA, von Dadelsen P, Singer J, Lee T, Rey E, Ross S, et al. The CHIPS randomized controlled trial (Control of hypertension in pregnancy study): is severe hypertension just an elevated blood pressure?. Hypertension 2016;68(5):1153-9.

Poon LC, Shennan A, Hyett JA, Kapur A, Hadar E, Divakar H, et al. The international federation of gynecology and obstetrics (FIGO) initiative on pre- eclampsia: a pragmatic guide for first-trimester screening and prevention. Int J Gynaecol Obstet. 2019;145(Suppl 1):1-33.

Ehrenthal DB, Jurkovitz C, Hoffman M, Jiang X, Weintraub WS. Prepregnancy body mass index as an independent risk factor for pregnancy-induced hypertension. J Women's Health. 2011;20(1):67-72.

Lewandowska M, Wieckowska B, Sajdak. Pre-pregnancy obesity, excessive gestational weight gain, and the risk of pregnancy-induced hypertension and gestational diabetes mellitus. J Clin Med. 2020;9(6):1980.

Sravani R, Reddy GP. HDP gestosis score as a predictor of PIH. Int J Clin Obstetr Gynaecol. 2022;(6):5.

Sovio U, Smith GC. Evaluation of a simple risk score to predict preterm pre‐eclampsia using maternal characteristics: a prospective cohort study. BJOG: Int J Obstetr Gynaecol. 2019;126(8):963-70.

Parthasarathy AKKA, Madhumitha J, Manohar S. An observational study of evaluation of extended first trimester screening test to predict early preterm pre eclampsia in pregnant women. Int J Reprod Contracept Obstet Gynecol. 2022;11(7):1988-93.

Goetzinger KR, Tuuli MG, Cahill AG, Macones GA, Odibo AO. Development and validation of a risk factor scoring system for first-trimester prediction of preeclampsia. Am J Perinatol. 201;31(12):1049-56.

American College of Obstetricians and Gynecologists. Low-dose aspirin use during pregnancy. ACOG Committee Opinion No. 743. Obstet Gynecol. 2018;132(01):254-6.

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Published

2024-06-27

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Original Research Articles